Üstün Bezgin Selin, Çakabay Taliye, Irak Kader, Koçyiğit Murat, Serin Keskineğe Bilge, Cevizci Raşit, Bayazıt Yıldırım Ahmet
Otorhinolaryngology Department, Istanbul Kanuni Sultan Süleyman Training and Research Hospital, Atakent mahallesi, Turgut Özal caddesi No: 1, Altınşehir/Küçükçekmece, 34303, Istanbul, Turkey.
Gastroenterology Department, Istanbul Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.
Eur Arch Otorhinolaryngol. 2017 Sep;274(9):3403-3405. doi: 10.1007/s00405-017-4656-y. Epub 2017 Jun 26.
The aim of the present study is to investigate the role of Helicobacter pylori in olfactory function. Thirty-six patients (mean age 38.5) aged between 18 and 55 years who were diagnosed with H. pylori by gastric biopsies and age- and sex-matched 30 healthy adults (mean age 33.6) were included in the study. All participants underwent a detailed ear-nose-throat examination including endoscopic examination of the nasal cavity and laryngeal area, and olfactory tests were performed using the Sniffin' Sticks, a 12-item screening test (Sniffin'Sticks; Burghart, Wedel, Germany) and odor scores were recorded. The mean odor score was 7.9 ± 1.7 (range 2-10) in the patient group and 10.3 ± 1.4 (range 6-12) in the control group. There were significant lower scores in the patient group compared to the control group (p < 0.05). In conclusion, it is apparent that there is an association of H. pylori infection with olfactory dysfunction. H. pylori infection should be considered as possible etiological factors in patients with olfactory dysfunction.
本研究的目的是探讨幽门螺杆菌在嗅觉功能中的作用。该研究纳入了36例年龄在18至55岁之间、经胃活检确诊为幽门螺杆菌感染的患者（平均年龄38.5岁），以及30名年龄和性别匹配的健康成年人（平均年龄33.6岁）。所有参与者均接受了详细的耳鼻喉检查，包括鼻腔和喉部区域的内镜检查，并使用Sniffin' Sticks进行嗅觉测试，这是一项包含12个项目的筛查测试（Sniffin'Sticks；德国韦德尔市的布尔哈特公司），并记录气味评分。患者组的平均气味评分为7.9±1.7（范围为2至10），对照组为10.3±1.4（范围为6至12）。与对照组相比，患者组的评分显著更低（p<0.05）。总之，显然幽门螺杆菌感染与嗅觉功能障碍有关。幽门螺杆菌感染应被视为嗅觉功能障碍患者可能的病因。
