Moulin Valerie, Palix Julie, Alameda Luis, Gholamrezaee M Mehdi, Baumann Philipp S, Gasser Jacques, Elowe Julien, Solida Alessandra, Conus Philippe
1 Unité de Recherche en Psychiatrie et Psychologie Légales, Institut de Psychiatrie légale, Département de Psychiatrie du Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse.
2 Service de Psychiatrie Générale, Service de Psychiatrie de Liaison et Centre de Neuroscience Psychiatrique, Département de Psychiatrie du Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse.
Can J Psychiatry. 2018 Jan;63(1):20-29. doi: 10.1177/0706743717718173. Epub 2017 Jun 28.
: An important proportion of patients with first episode psychosis behave in a violent, hetero-aggressive manner. This study aims to explore the association between insight and violent behavior (VB), and insight evolution in the follow-up period.
: The study was carried out with a prospective cohort of 265 patients recruited from the early treatment and intervention for psychotic disorders program, and followed for a 3-year period. Insight assessing is based on a 3-item scale and the insight item in Positive and Negative Syndrome Scale (PANSS). VBs were evaluated by case managers, information from forensic services and through a record of VBs noted during hospitalization. Univariate and multivariate logistic regression analyses, t-tests and correlations were conducted.
: The significant effect of insight as a factor associated with VBs that was found in univariate analyses disappears after controlling for the effect of positive symptoms, substance addiction diagnosis, impulsivity and treatment compliance.
: If patient insight in their illness develops positively during treatment, our results suggest that the risk of VBs occurring is not influenced by insight level. On the other hand, it is significantly linked to substance abuse and impulsivity, which might implicate focusing on these 2 dimensions in preventive strategies. Insight impact on VB should be further explored in more focused prospective analyses.
首发精神病患者中有相当一部分表现出暴力、异质性攻击行为。本研究旨在探讨自知力与暴力行为(VB)之间的关联,以及随访期间自知力的演变。
该研究对从精神病障碍早期治疗与干预项目中招募的265名患者进行了前瞻性队列研究,随访期为3年。自知力评估基于一个3项量表以及阳性和阴性症状量表(PANSS)中的自知力项目。暴力行为由个案管理员评估,法医服务信息以及通过住院期间记录的暴力行为记录进行评估。进行了单因素和多因素逻辑回归分析、t检验和相关性分析。
在控制阳性症状、物质成瘾诊断、冲动性和治疗依从性的影响后,单因素分析中发现的自知力作为与暴力行为相关因素的显著效应消失。
如果患者在治疗期间对疾病的自知力得到积极发展,我们的结果表明暴力行为发生的风险不受自知力水平的影响。另一方面,它与物质滥用和冲动性显著相关,这可能意味着在预防策略中应关注这两个维度。自知力对暴力行为的影响应在更有针对性的前瞻性分析中进一步探讨。