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Impulsivity in early psychosis: A complex link with violent behaviour and a target for intervention.早期精神病中的冲动性:与暴力行为的复杂联系及其干预目标。
Eur Psychiatry. 2018 Mar;49:30-36. doi: 10.1016/j.eurpsy.2017.12.003. Epub 2018 Jan 30.
2
Violent behaviour in early psychosis patients: Can we identify clinical risk profiles?早期精神病患者的暴力行为:我们能否识别临床风险特征?
Early Interv Psychiatry. 2019 Jun;13(3):517-524. doi: 10.1111/eip.12512. Epub 2017 Nov 15.
3
Much ado about everything: A literature review of insight in first episode psychosis and schizophrenia.小题大做:首发精神病和精神分裂症洞察力的文献综述
Eur Psychiatry. 2017 Jan;39:73-79. doi: 10.1016/j.eurpsy.2016.07.007. Epub 2016 Dec 16.
4
Insight as a social identity process in the evolution of psychosocial functioning in the early phase of psychosis.洞察力作为精神病早期心理社会功能演变中的一种社会认同过程。
Psychol Med. 2017 Mar;47(4):718-729. doi: 10.1017/S0033291716002506. Epub 2016 Nov 21.
5
New Clinically Relevant Findings about Violence by People with Schizophrenia.关于精神分裂症患者暴力行为的新的临床相关发现。
Can J Psychiatry. 2017 Feb;62(2):86-93. doi: 10.1177/0706743716648300. Epub 2016 Jul 11.
6
[Insight and psychiatric dangerousness: A review of the literature].[洞察与精神科危险性:文献综述]
Encephale. 2017 Apr;43(2):146-153. doi: 10.1016/j.encep.2016.01.010. Epub 2016 May 20.
7
Assertive outreach for "difficult to engage" patients: A useful tool for a subgroup of patients in specialized early psychosis intervention programs.积极主动地接触“难以接触”的患者:专门的早期精神病干预项目中患者亚组的有用工具。
Psychiatry Res. 2016 May 30;239:212-9. doi: 10.1016/j.psychres.2016.03.010. Epub 2016 Mar 5.
8
Childhood sexual and physical abuse: age at exposure modulates impact on functional outcome in early psychosis patients.童年期性虐待和身体虐待:暴露年龄调节对早期精神病患者功能结局的影响。
Psychol Med. 2015 Oct;45(13):2727-36. doi: 10.1017/S0033291715000690.
9
Is good insight associated with depression among patients with schizophrenia? Systematic review and meta-analysis.精神分裂症患者的洞察力良好与抑郁有关吗?系统评价与荟萃分析。
Schizophr Res. 2015 Mar;162(1-3):234-47. doi: 10.1016/j.schres.2015.01.003. Epub 2015 Jan 24.
10
Treatment and violent behavior in persons with first episode psychosis during a 10-year prospective follow-up study.在一项为期10年的前瞻性随访研究中,首发精神病患者的治疗与暴力行为
Schizophr Res. 2014 Jul;156(2-3):272-6. doi: 10.1016/j.schres.2014.04.010. Epub 2014 May 15.

[一组早期精神病患者的洞察力与暴力行为]

[Insight and Violent Behavior in a Cohort of Early Psychosis Patients].

作者信息

Moulin Valerie, Palix Julie, Alameda Luis, Gholamrezaee M Mehdi, Baumann Philipp S, Gasser Jacques, Elowe Julien, Solida Alessandra, Conus Philippe

机构信息

1 Unité de Recherche en Psychiatrie et Psychologie Légales, Institut de Psychiatrie légale, Département de Psychiatrie du Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse.

2 Service de Psychiatrie Générale, Service de Psychiatrie de Liaison et Centre de Neuroscience Psychiatrique, Département de Psychiatrie du Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse.

出版信息

Can J Psychiatry. 2018 Jan;63(1):20-29. doi: 10.1177/0706743717718173. Epub 2017 Jun 28.

DOI:10.1177/0706743717718173
PMID:28655283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5788119/
Abstract

OBJECTIVES

: An important proportion of patients with first episode psychosis behave in a violent, hetero-aggressive manner. This study aims to explore the association between insight and violent behavior (VB), and insight evolution in the follow-up period.

METHOD

: The study was carried out with a prospective cohort of 265 patients recruited from the early treatment and intervention for psychotic disorders program, and followed for a 3-year period. Insight assessing is based on a 3-item scale and the insight item in Positive and Negative Syndrome Scale (PANSS). VBs were evaluated by case managers, information from forensic services and through a record of VBs noted during hospitalization. Univariate and multivariate logistic regression analyses, t-tests and correlations were conducted.

RESULTS

: The significant effect of insight as a factor associated with VBs that was found in univariate analyses disappears after controlling for the effect of positive symptoms, substance addiction diagnosis, impulsivity and treatment compliance.

CONCLUSION

: If patient insight in their illness develops positively during treatment, our results suggest that the risk of VBs occurring is not influenced by insight level. On the other hand, it is significantly linked to substance abuse and impulsivity, which might implicate focusing on these 2 dimensions in preventive strategies. Insight impact on VB should be further explored in more focused prospective analyses.

摘要

目的

首发精神病患者中有相当一部分表现出暴力、异质性攻击行为。本研究旨在探讨自知力与暴力行为(VB)之间的关联,以及随访期间自知力的演变。

方法

该研究对从精神病障碍早期治疗与干预项目中招募的265名患者进行了前瞻性队列研究,随访期为3年。自知力评估基于一个3项量表以及阳性和阴性症状量表(PANSS)中的自知力项目。暴力行为由个案管理员评估,法医服务信息以及通过住院期间记录的暴力行为记录进行评估。进行了单因素和多因素逻辑回归分析、t检验和相关性分析。

结果

在控制阳性症状、物质成瘾诊断、冲动性和治疗依从性的影响后,单因素分析中发现的自知力作为与暴力行为相关因素的显著效应消失。

结论

如果患者在治疗期间对疾病的自知力得到积极发展,我们的结果表明暴力行为发生的风险不受自知力水平的影响。另一方面,它与物质滥用和冲动性显著相关,这可能意味着在预防策略中应关注这两个维度。自知力对暴力行为的影响应在更有针对性的前瞻性分析中进一步探讨。