Abushouk Abdelrahman Ibrahim, Salem Amr Muhammad Abdo, Abdel-Daim Mohamed M
Faculty of Medicine, Ain Shams University, Cairo, Egypt.
NovaMed Medical Research Association, Cairo, Egypt.
Iran J Basic Med Sci. 2017 May;20(5):503-510. doi: 10.22038/IJBMS.2017.8674.
Cardiovascular disorders are the leading cause of mortality worldwide. () is a commonly used plant in traditional medicine. In recent studies, showed antiarrhythmic, antihypertensive, anticholinergic, and cardioprotective effects. We reviewed the literature to explore the possible prophylactic and therapeutic roles of in cardiovascular medicine. A computer literature search was conducted to identify all relevant studies that have investigated the role of in prevention or treatment of cardiovascular diseases. We also searched the citations of the retrieved articles. Using a systematic approach, we conducted a scoping review that included a total of 37 articles. Twelve studies examined the antihypertensive effects of , seven studies investigated its antiarrhythmic effects, while its inotropic and cardioprotective effects were evaluated in four and eight studies, respectively. showed a beneficial effect in reducing blood pressure, enhancing cardiac contractility, and protection from reperfusion injury. However, the mechanisms of these effects are still under investigation. Moreover, it could modify major risk factors for cardiovascular disorders, such as oxidative stress, hyperglycemia, and hyperlipidemia. Further studies are needed to translate these findings into effective cardiovascular medications.
心血管疾病是全球主要的死亡原因。（）是传统医学中常用的一种植物。在最近的研究中，（）显示出抗心律失常、抗高血压、抗胆碱能和心脏保护作用。我们回顾了文献，以探讨（）在心血管医学中可能的预防和治疗作用。进行了计算机文献检索，以识别所有研究（）在预防或治疗心血管疾病中作用的相关研究。我们还搜索了检索到的文章的参考文献。采用系统的方法，我们进行了一项范围综述，共纳入37篇文章。12项研究考察了（）的降压作用，7项研究调查了其抗心律失常作用，而分别有4项和8项研究评估了其正性肌力作用和心脏保护作用。（）在降低血压、增强心肌收缩力和预防再灌注损伤方面显示出有益作用。然而，这些作用的机制仍在研究中。此外，它可以改变心血管疾病的主要危险因素，如氧化应激、高血糖和高血脂。需要进一步的研究将这些发现转化为有效的心血管药物。
