Department of Oral & Maxillofacial Surgery, Public Health Service, Gävle, Sweden.
Centre for Research and Development, Uppsala University/Gävleborg County Council, Gävleborg, Sweden.
Clin Implant Dent Relat Res. 2017 Oct;19(5):884-894. doi: 10.1111/cid.12512. Epub 2017 Jun 28.
The optimal ratio of deproteinized bovine bone (DPBB) and autogenous bone (AB) for lateral augmentation is presently unknown.
To evaluate implant treatment outcome and radiological graft changes after lateral ridge augmentation with 2 different mixtures of DPBB and AB, 2 years after functional loading.
Thirteen patients were included in a split mouth, randomized, controlled trial. Four partially edentulous and 10 totally edentulous jaws with an alveolar ridge width of <4 mm were augmented with a graft mixture of 90:10 (DPBB:AB) on one side and 60:40 (DPBB:AB) on the contra lateral side. Graft width changes were measured on CBCT scans at different time points. Implant survival and success rates were calculated. Resonance frequency analysis and marginal bone measurements were performed after 2 years of loading.
The survival rate was 94.4% for implants installed in the 90:10 and 100% for implants installed in the 60:40. There were no statistically significant differences in survival rate or success rate between the mixtures. The width was 5.7 mm and 6.2 mm, respectively for the 2 groups without any significant difference between the groups after 2 years of loading. There was a significant difference in graft reduction between the groups, 54.4% (90:10) and 37.5% (60:40), respectively. There were no statistically significant differences in implant stability or marginal bone levels at any time points.
The 2 treatment modalities may be successfully used for lateral ridge augmentation and presented good clinical results after 2 years of loading. However, long-term RCTs are required before final conclusions can be provided on this specific topic.
目前尚不清楚脱蛋白牛骨(DPBB)和自体骨(AB)用于外侧增强的最佳比例。
评估在功能加载 2 年后,使用 2 种不同 DPBB 和 AB 混合物进行外侧嵴增强后的种植体治疗效果和影像学移植物变化。
13 名患者参与了一项随机对照、双侧的分割口腔试验。4 个部分缺牙和 10 个完全缺牙的牙槽嵴宽度<4mm 的患者,一侧用 90:10(DPBB:AB)的混合物进行移植,另一侧用 60:40(DPBB:AB)的混合物进行移植。在不同时间点的 CBCT 扫描上测量移植物宽度的变化。计算种植体的存活率和成功率。在负荷 2 年后进行共振频率分析和边缘骨测量。
在安装 90:10 混合物的种植体中,存活率为 94.4%,在安装 60:40 混合物的种植体中,存活率为 100%。在存活率或成功率方面,这两种混合物之间没有统计学上的显著差异。2 年后,两组的宽度分别为 5.7mm 和 6.2mm,两组之间无显著差异。在移植骨减少方面,两组之间有显著差异,分别为 54.4%(90:10)和 37.5%(60:40)。在任何时间点,种植体稳定性或边缘骨水平均无统计学差异。
这两种治疗方法均可成功用于外侧嵴增强,并在负荷 2 年后取得良好的临床效果。然而,在对此特定主题作出最终结论之前,还需要进行长期的 RCT。