• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

膝关节肿瘤及翻修手术中的大型假体

Megaprosthesis of the knee in tumor and revision surgery.

作者信息

Pala E, Trovarelli G, Angelini A, Maraldi M, Berizzi A, Ruggieri Pietro

机构信息

.

出版信息

Acta Biomed. 2017 Jun 7;88(2S):129-138. doi: 10.23750/abm.v88i2-S.6523.

DOI:10.23750/abm.v88i2-S.6523
PMID:28657574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6179001/
Abstract

The introduction of multidisciplinary approach with chemo and radiotherapy, the advances in surgical and the improvements of diagnostic techniques allowed limb salvage surgery in most cases of bone sarcomas instead of amputation. Modular megaprostheses are the most common method of reconstruction after segmental resection of the long bones in the extremities for their availability, immediate fixation, early weight bearing, good function. Despite the advances in materials and implant designs, these systems have an high incidence of complications. Aim of this study was to report the experience on mega-prostheses implanted around the knee in tumor and revision surgery to analyze: the most frequent used current systems, the problems of stems fixation, extensor mechanism reconstructions in proximal tibia resections and the preservation of growth of the lower extremity in children.

摘要

多学科化疗和放疗方法的引入、外科手术的进展以及诊断技术的改进,使得在大多数骨肉瘤病例中可以进行保肢手术而非截肢。模块化大假体因其可用性、即刻固定、早期负重和良好功能,是四肢长骨节段切除术后最常用的重建方法。尽管材料和植入物设计有所进步,但这些系统并发症发生率很高。本研究的目的是报告在肿瘤和翻修手术中植入膝关节周围大假体的经验,以分析:当前最常用的系统、柄部固定问题、胫骨近端切除术中伸肌机制重建以及儿童下肢生长的保留情况。

相似文献

1
Megaprosthesis of the knee in tumor and revision surgery.膝关节肿瘤及翻修手术中的大型假体
Acta Biomed. 2017 Jun 7;88(2S):129-138. doi: 10.23750/abm.v88i2-S.6523.
2
What Are the Long-term Results of MUTARS Modular Endoprostheses for Reconstruction of Tumor Resection of the Distal Femur and Proximal Tibia?用于股骨远端和胫骨近端肿瘤切除重建的MUTARS模块化假体的长期效果如何?
Clin Orthop Relat Res. 2017 Mar;475(3):708-718. doi: 10.1007/s11999-015-4644-8.
3
[Periprosthetic Infection of the Knee Megaprosthesis following a Resection of Malignant Tumours around the Knee].[膝关节周围恶性肿瘤切除术后膝关节大假体周围感染]
Acta Chir Orthop Traumatol Cech. 2017;84(1):46-51.
4
Survival of total knee replacement with a megaprosthesis after bone tumor resection.骨肿瘤切除术后使用巨型假体的全膝关节置换术的生存率。
J Bone Joint Surg Am. 2006 Jun;88(6):1285-93. doi: 10.2106/JBJS.E.00553.
5
Distal femur and proximal tibia replacement with megaprosthesis in revision knee arthroplasty: a limb-saving procedure.在膝关节翻修术中使用 megaprosthesis 置换股骨远端和胫骨近端:一种保肢手术。
Knee Surg Sports Traumatol Arthrosc. 2012 Dec;20(12):2513-8. doi: 10.1007/s00167-012-1945-2. Epub 2012 Mar 6.
6
Influence of implant length and bone defect situation on primary stability after distal femoral replacement in vitro.股骨远端置换术后种植体长度和骨缺损情况对体外初期稳定性的影响
Knee. 2017 Oct;24(5):1016-1024. doi: 10.1016/j.knee.2017.07.010. Epub 2017 Aug 6.
7
Survival, complications and functional outcomes of cemented megaprostheses for high-grade osteosarcoma around the knee.膝关节周围高级别骨肉瘤骨水泥型大假体置换的生存率、并发症及功能结果
Int Orthop. 2018 Apr;42(4):927-938. doi: 10.1007/s00264-018-3770-9. Epub 2018 Feb 9.
8
Revision of broken knee megaprostheses: new solution to old problems.翻修破损的膝关节假体:解决老问题的新方法。
Clin Orthop Relat Res. 2010 Nov;468(11):2904-13. doi: 10.1007/s11999-010-1409-2.
9
Tibial revision knee arthroplasty: influence of modular stems on implant fixation and bone flexibility in AORI Type T2a defects.胫骨翻修膝关节置换术:模块化柄对AORI T2a型缺损中植入物固定和骨柔韧性的影响。
Int J Artif Organs. 2016 Nov 29;39(10):534-540. doi: 10.5301/ijao.5000530. Epub 2016 Nov 9.
10
[Complications from the hinged GUEPAR prosthesis after resection of knee tumor. 102 cases].[膝关节肿瘤切除术后铰链式GUEPAR假体的并发症。102例]
Rev Chir Orthop Reparatrice Appar Mot. 1998 Nov;84(7):628-37.

引用本文的文献

1
Reconstructive Arthroplasty for Malignant Bone Tumors of the Knee-A Single-Center Experience of Functionality and Quality of Life.膝关节恶性骨肿瘤的重建关节成形术——单中心功能与生活质量经验
J Clin Med. 2025 Sep 5;14(17):6287. doi: 10.3390/jcm14176287.
2
Successful limb-salvage procedure using a bioexpandable prosthesis after infected primary reconstruction of the distal femur in a skeletally immature patient: a case report.在一名骨骼未成熟患者中,对股骨远端进行感染后的初次重建时,使用生物可扩张假体成功保肢的病例报告。
World J Surg Oncol. 2025 Apr 2;23(1):116. doi: 10.1186/s12957-025-03759-5.
3
The role of the medial head of the gastrocnemius myocutaneous flap transfer in the management of prosthesis exposure and deep joint infection following total knee arthroplasty.腓肠肌内侧头肌皮瓣转移术在全膝关节置换术后假体暴露及深部关节感染处理中的作用
Arch Orthop Trauma Surg. 2024 Dec 12;145(1):26. doi: 10.1007/s00402-024-05679-7.
4
Shared decision making in primary malignant bone tumour surgery around the knee in children and young adults: protocol for a prospective study.儿童和青年膝关节周围原发性恶性骨肿瘤手术中的共同决策:一项前瞻性研究方案。
J Orthop Surg Res. 2024 Nov 2;19(1):714. doi: 10.1186/s13018-024-05192-y.
5
Postoperative challenges addressed through nursing care of patients receiving lower extremity tumor prosthesis.通过对接受下肢肿瘤假体患者的护理来应对术后挑战。
BMC Nurs. 2024 Oct 4;23(1):714. doi: 10.1186/s12912-024-02400-2.
6
Risk Factors and Management of Prosthetic Joint Infections in Megaprostheses-A Review of the Literature.大假体中人工关节感染的危险因素与管理——文献综述
Antibiotics (Basel). 2023 Dec 26;13(1):25. doi: 10.3390/antibiotics13010025.
7
Osseointegration reduces aseptic loosening of primary distal femoral implants in pediatric and adolescent osteosarcoma patients: a retrospective clinical and radiographic study.骨整合减少了儿童和青少年骨肉瘤患者初次股骨远端植入物的无菌性松动:一项回顾性临床和影像学研究。
Eur J Orthop Surg Traumatol. 2023 Dec;33(8):3585-3596. doi: 10.1007/s00590-023-03590-2. Epub 2023 May 29.
8
High Risk for Persistent Peri-Prosthetic Infection and Amputation in Mega-Prosthesis Reconstruction.大假体重建中持续性假体周围感染和截肢的高风险
J Clin Med. 2023 May 20;12(10):3575. doi: 10.3390/jcm12103575.
9
The history of resection prosthesis.切除假体的历史。
Int Orthop. 2023 Mar;47(3):873-883. doi: 10.1007/s00264-023-05698-w. Epub 2023 Jan 18.
10
Apparent trends in the use of femoral megaprostheses: an analysis from the National Joint Registry.股骨大型假体使用的明显趋势:来自国家关节注册中心的分析
Arthroplasty. 2022 Dec 1;4(1):50. doi: 10.1186/s42836-022-00150-7.

本文引用的文献

1
Lower limb reconstruction in tumor patients using modular silver-coated megaprostheses with regard to perimegaprosthetic joint infection: a case series, including 100 patients and review of the literature.关于肿瘤患者使用模块化镀银大假体进行下肢重建及假体周围关节感染的病例系列研究:100例患者及文献综述
Arch Orthop Trauma Surg. 2017 Feb;137(2):149-153. doi: 10.1007/s00402-016-2584-8. Epub 2016 Oct 25.
2
Silver-Coated Hip Megaprosthesis in Oncological Limb Savage Surgery.肿瘤肢体挽救手术中的镀银髋关节大假体
Biomed Res Int. 2016;2016:9079041. doi: 10.1155/2016/9079041. Epub 2016 Aug 23.
3
Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses after Tumor Resection.肿瘤切除后重建假体固定的加压骨整合的放射学评估
Biomed Res Int. 2015;2015:513939. doi: 10.1155/2015/513939. Epub 2015 Jul 22.
4
Infected Prostheses after Lower-Extremity Bone Tumor Resection: Clinical Outcomes of 100 Patients.下肢骨肿瘤切除术后感染性假体:100例患者的临床结果
Surg Infect (Larchmt). 2015 Jun;16(3):267-75. doi: 10.1089/sur.2014.085. Epub 2015 Mar 26.
5
Survival of modern knee tumor megaprostheses: failures, functional results, and a comparative statistical analysis.现代膝关节肿瘤假体的生存率:失败情况、功能结果及比较性统计分析
Clin Orthop Relat Res. 2015 Mar;473(3):891-9. doi: 10.1007/s11999-014-3699-2.
6
Survival of current production tumor endoprostheses: complications, functional results, and a comparative statistical analysis.当前生产的肿瘤假体的存活率:并发症、功能结果和比较统计分析。
J Surg Oncol. 2013 Nov;108(6):403-8. doi: 10.1002/jso.23414. Epub 2013 Sep 4.
7
Long-term survival of cemented distal femoral endoprostheses with a hydroxyapatite-coated collar: a histological study and a radiographic follow-up.带羟基磷灰石涂层的骨水泥型股骨远端假体的长期生存:组织学研究和影像学随访。
J Bone Joint Surg Am. 2013 Sep 4;95(17):1569-75. doi: 10.2106/JBJS.L.00362.
8
Cemented versus cementless endoprostheses for lower limb salvage surgery.用于下肢保肢手术的骨水泥型与非骨水泥型假体
J BUON. 2013 Apr-Jun;18(2):496-503.
9
Outcome of expandable prostheses in children.儿童可扩张假体的治疗结果。
J Pediatr Orthop. 2013 Apr-May;33(3):244-53. doi: 10.1097/BPO.0b013e318286c178.
10
Compress knee arthroplasty has 80% 10-year survivorship and novel forms of bone failure.膝关节压缩成形术的 10 年存活率为 80%,且存在新型的骨失效形式。
Clin Orthop Relat Res. 2013 Mar;471(3):774-83. doi: 10.1007/s11999-012-2635-6.