Fairhurst M M
S Afr Med J. 1985 Oct 26;Suppl:29.
The coexistence of anxiety and depression as one syndrome is well documented. Benzodiazepines are not effective in the treatment of endogenous depression where tricyclic and newer antidepressants are more effective. However, they do combat the symptoms of non-endogenous depression and many of those found in anxiety disorders, including depressed mood, i.e. they may elevate the depressed mood that occurs secondary to anxiety. A study using bromazepam undertaken in 1984 by Roche with general practitioners confirmed this trend towards normalization of mood.
焦虑和抑郁作为一种综合征并存已有充分记录。苯二氮䓬类药物对治疗内源性抑郁症无效,而三环类和新型抗抑郁药在治疗内源性抑郁症方面更有效。然而,它们确实能对抗非内源性抑郁症的症状以及焦虑症中出现的许多症状,包括情绪低落,也就是说,它们可能会改善继发于焦虑的情绪低落。1984年罗氏公司与全科医生合作进行的一项使用溴西泮的研究证实了情绪趋于正常化的这一趋势。