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啮齿动物社会行为的神经解剖学基础:前额皮质内侧及其投射模式。

Neuroanatomical Substrates of Rodent Social Behavior: The Medial Prefrontal Cortex and Its Projection Patterns.

机构信息

Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Daegu, South Korea.

出版信息

Front Neural Circuits. 2017 Jun 13;11:41. doi: 10.3389/fncir.2017.00041. eCollection 2017.

DOI:10.3389/fncir.2017.00041
PMID:28659766
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5468389/
Abstract

Social behavior encompasses a number of distinctive and complex constructs that form the core elements of human imitative culture, mainly represented as either affiliative or antagonistic interactions with conspecifics. Traditionally considered in the realm of psychology, social behavior research has benefited from recent advancements in neuroscience that have accelerated identification of the neural systems, circuits, causative genes and molecular mechanisms that underlie distinct social cognitive traits. In this review article, I summarize recent findings regarding the neuroanatomical substrates of key social behaviors, focusing on results from experiments conducted in rodent models. In particular, I will review the role of the medial prefrontal cortex (mPFC) and downstream subcortical structures in controlling social behavior, and discuss pertinent future research perspectives.

摘要

社会行为包含了许多独特而复杂的结构,这些结构构成了人类模仿文化的核心要素,主要表现为与同类的亲和或敌对互动。传统上被认为属于心理学范畴,社会行为研究受益于神经科学的最新进展,这些进展加速了识别神经系统、回路、因果基因和分子机制的过程,这些都是不同社会认知特征的基础。在这篇综述文章中,我总结了最近关于关键社会行为神经解剖学基础的发现,重点介绍了在啮齿动物模型中进行的实验结果。特别是,我将回顾内侧前额叶皮层(mPFC)和下游皮质下结构在控制社会行为方面的作用,并讨论相关的未来研究视角。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1314/5468389/1596f59889e6/fncir-11-00041-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1314/5468389/1596f59889e6/fncir-11-00041-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1314/5468389/1596f59889e6/fncir-11-00041-g0001.jpg

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