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[免疫球蛋白测定在慢性肝病中的诊断意义。II. 免疫球蛋白变化与活动程度的关系(作者译)]

[The diagnostic significance of immunoglobulin determination in chronic liver diseases. II. Relationships between immunoglobulin changes and degree of activity (author's transl)].

作者信息

Ortmans H, Wildhirt E, Welcke U, Tücke M

出版信息

MMW Munch Med Wochenschr. 1975 Dec 12;117(50):1975-8.

PMID:2866
Abstract

The relationship between the immunograms and aminotransferases, gamma-GT and AP were examined in 715 patients with hepatobiliary diseases closely confirmed by histomorphological criteria and a series of 60 normal subjects. The normal subjects showed positive relationships. These are largely lacking in acute and protracted courses and in chronic aggressive hepatitis. Only relationships of the individual immunoglobulins between themselves can be demonstrated in the aggressive chronic types. Positive relationships are present between immunograms and aminotransferases, gamma-GT and AP in the group with fatty livers, and so are other highly significant positive relationships in toxic hepatitis and toxic cirrhoses of the liver.

摘要

对715例经组织形态学标准确诊的肝胆疾病患者以及60例正常对照者,研究了免疫图谱与转氨酶、γ-谷氨酰转移酶(gamma-GT)及碱性磷酸酶(AP)之间的关系。正常对照者呈现出正相关关系。在急性和迁延性病程以及慢性侵袭性肝炎中,这些关系大多不存在。仅在侵袭性慢性类型中可证明各免疫球蛋白之间的关系。在脂肪肝组中,免疫图谱与转氨酶、gamma-GT及AP之间存在正相关关系,在中毒性肝炎和中毒性肝硬化中也存在其他高度显著的正相关关系。

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