Vicentini Joao R T, Martinez-Salazar Edgar L, Chang Connie Y, Bredella Miriam A, Rosenthal Daniel I, Torriani Martin
Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, YAW 6048, Boston, MA, 02114, USA.
Skeletal Radiol. 2017 Oct;46(10):1367-1378. doi: 10.1007/s00256-017-2699-1. Epub 2017 Jun 28.
Hemispherical spondylosclerosis (HS) is a rare degenerative entity characterized by dome-shaped sclerosis of a single vertebral body that may pose a diagnostic dilemma. The goal of this study was to describe the MR imaging features of HS.
We identified spine radiographs and CT examinations of subjects with HS who also had MR imaging for correlation. Two musculoskeletal radiologists independently assessed sclerosis characteristics, presence of endplate erosions, marrow signal intensity, and disk degeneration (Pfirrmann scale).
We identified 11 subjects (six males, five females, mean 48 ± 10 years) with radiographic/CT findings of HS. The most commonly affected vertebral body was L4 (6/11; 55%). On MR imaging, variable signal intensity was noted, being most commonly low on T1 (8/11, 73%) and high on fat-suppressed T2-weighted (8/11, 73%) images. In two subjects, diffuse post-contrast enhancement was seen in the lesion. Moderate disk degeneration and endplate bone erosions adjacent to sclerosis were present in all subjects. Erosions of the opposite endplate were present in two subjects (2/11, 18%). CT data from nine subjects showed the mean attenuation value of HS was 472 ± 96 HU.
HS appearance on MR imaging is variable and may not correlate with the degree of sclerosis seen on radiographs or CT. Disk degenerative changes and asymmetric endplate erosions are consistent markers of HS.
半球形椎体硬化症(HS)是一种罕见的退行性病变,其特征为单个椎体呈圆顶状硬化,这可能会造成诊断上的难题。本研究的目的是描述HS的磁共振成像(MR)特征。
我们确定了患有HS且同时进行了MR成像以作对照的受试者的脊柱X线片和CT检查结果。两名肌肉骨骼放射科医生独立评估硬化特征、终板侵蚀的存在情况、骨髓信号强度和椎间盘退变(Pfirrmann分级)。
我们确定了11名受试者(6名男性,5名女性,平均年龄48±10岁),其X线片/CT检查结果显示为HS。最常受累的椎体是L4(6/11;55%)。在MR成像上,观察到信号强度各异,在T1加权像上最常见为低信号(8/11,73%),在脂肪抑制T2加权像上为高信号(8/11,73%)。在两名受试者中,病变内可见弥漫性增强后强化。所有受试者均存在中度椎间盘退变以及与硬化相邻的终板骨质侵蚀。两名受试者(2/11,18%)存在对侧终板侵蚀。9名受试者的CT数据显示HS的平均衰减值为472±96HU。
HS在MR成像上的表现各异,可能与X线片或CT上所见的硬化程度无关。椎间盘退变改变和不对称的终板侵蚀是HS的一致特征。