Zdrojewicz Zygmunt, Szyca Marta, Popowicz Ewa, Michalik Tomasz, Śmieszniak Bartłomiej
Medical University of Wrocław, Poland: Chair and Department of Endocrinology, Diabetology and Isotop Therapy.
Medical University of Wrocław, Poland: Medical Faculty.
Pol Merkur Lekarski. 2017 Jun 23;42(252):227-230.
The purpose of this article is to introduce the role of turmeric in medicine and summarize the current state of research on its applications. Turmeric (Curcuma longa) has had a wide range of uses in middle eastern and orietnal traditional medicine. Currently, however, its use has been truncated to a common cooking spice, despite numerous studies pointing to its healing properties and possible use in the treatment of many diseases. The main focus is on curcumin, a polyphenol which serves as the biologically active component of turmeric. Curcumin's anti-inflammatory effects have been well documented in medical studies, with wide ranging applications from the treatment of rheumatologic diseases such as arthritis to dermatology, with significant effects in the treatment of psoriasis, acne and in relieving of itching. In addition to the effect of pro-inflammatory cytokines, curcumin can also accelerate healing of skin wounds. Apart from controlling the body's inflammatory response, curcumin has a bacteriostatic effect, which has been shown to be an important factor in the treatment of diseases with complex etiology. Additionally, studies show that curcumin's effects on oncogenesis, the process of metastasis, angiogenesis, apoptosis or response to cytostatic drugs have yielded promising results. It has been confirmed that its antioxidant effect correlates with a decrease in LDL levels in blood and to a reduced risk of atherosclerosis. Curcumin consumption has also been shown to have a vasodilating effect through its indirect impact on prostacyclins and directly on vascular endothelium. Many of the mention medicinal properties of turmeric are still the subject of research and debate; as such, only some of them have entered the phase of clinical trials.
本文旨在介绍姜黄在医学中的作用，并总结其应用的研究现状。姜黄（Curcuma longa）在中东和东方传统医学中有广泛应用。然而目前，尽管众多研究指出其具有治疗功效且可能用于治疗多种疾病，但它已沦为一种普通的烹饪香料。主要关注点是姜黄素，一种作为姜黄生物活性成分的多酚。姜黄素的抗炎作用在医学研究中已有充分记载，其应用范围广泛，从治疗类风湿性疾病如关节炎到皮肤科，在治疗牛皮癣、痤疮以及缓解瘙痒方面都有显著效果。除了对促炎细胞因子的作用外，姜黄素还能加速皮肤伤口愈合。除了控制身体的炎症反应，姜黄素还具有抑菌作用，这已被证明是治疗病因复杂疾病的一个重要因素。此外，研究表明姜黄素对肿瘤发生、转移过程、血管生成、细胞凋亡或对细胞毒性药物的反应所产生的影响已取得了有前景的结果。已证实其抗氧化作用与血液中低密度脂蛋白水平的降低以及动脉粥样硬化风险的降低相关。食用姜黄素还通过其对前列环素的间接影响以及对血管内皮的直接作用而具有血管舒张作用。姜黄许多上述药用特性仍在研究和争论之中；因此，其中只有一些已进入临床试验阶段。
