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姜黄( turmeric)及其活性成分姜黄素对天然和化学毒性的解毒或保护作用:综述。

Antidotal or protective effects of Curcuma longa (turmeric) and its active ingredient, curcumin, against natural and chemical toxicities: A review.

机构信息

Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad Iran.

Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Biomed Pharmacother. 2018 Mar;99:411-421. doi: 10.1016/j.biopha.2018.01.072.

DOI:10.1016/j.biopha.2018.01.072
PMID:29367110
Abstract

Curcuma longa is a rhizomatous perennial herb that belongs to the family Zingiberaceae, native to South Asia and is commonly known as turmeric. It is used as herbal remedy due to the prevalent belief that the plant has medical properties. C. longa possesses different effects such as antioxidant, anti-tumor, antimicrobial, anti-inflammatory, wound healing, and gastroprotective activities. The recent studies have shown that C. longa and curcumin, its important active ingredient, have protective effects against toxic agents. In this review article, we collected in vitro and animal studies which are related to protective effects of turmeric and its active ingredient against natural and chemical toxic agents.

摘要

姜黄是姜科姜黄属的一种多年生草本植物,原产于南亚,通常被称为姜黄。由于普遍认为该植物具有药用特性,因此被用作草药。姜黄具有不同的作用,如抗氧化、抗肿瘤、抗菌、抗炎、伤口愈合和胃保护作用。最近的研究表明,姜黄及其重要的活性成分姜黄素对有毒物质具有保护作用。在这篇综述文章中,我们收集了与姜黄及其活性成分对天然和化学有毒物质的保护作用有关的体外和动物研究。

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1
Antidotal or protective effects of Curcuma longa (turmeric) and its active ingredient, curcumin, against natural and chemical toxicities: A review.姜黄( turmeric)及其活性成分姜黄素对天然和化学毒性的解毒或保护作用:综述。
Biomed Pharmacother. 2018 Mar;99:411-421. doi: 10.1016/j.biopha.2018.01.072.
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A Comprehensive Review on Physiological Effects of Curcumin.姜黄素的生理效应综合评价
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[Neuroprotective effects of curcumin].[姜黄素的神经保护作用]
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Effect of the proportion of curcuminoids on the gastroprotective action of L. in rats.姜黄素比例对姜黄素保护大鼠胃作用的影响。
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引用本文的文献

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Curcumin, an active component of turmeric: biological activities, nutritional aspects, immunological, bioavailability, and human health benefits - a comprehensive review.姜黄素,姜黄的一种活性成分:生物学活性、营养特性、免疫学、生物利用度及对人类健康的益处——综述
Front Immunol. 2025 Aug 21;16:1603018. doi: 10.3389/fimmu.2025.1603018. eCollection 2025.
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Protective role of curcumin and selenium nanoparticles against aluminium chloride-induced hepatorenal toxicity in rats.姜黄素和硒纳米颗粒对氯化铝诱导的大鼠肝肾毒性的保护作用
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Curcumin protects extracellular matrix to maintain microenvironmental stability inhibiting colon cancer metastasis through HPSE/IL-6/STAT5 axis.
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Naturwissenschaften. 2025 Jun 4;112(4):47. doi: 10.1007/s00114-025-01988-y.
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Naunyn Schmiedebergs Arch Pharmacol. 2025 May 7. doi: 10.1007/s00210-025-04239-z.
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Green Synthesis of Curcumin Loaded Carbon Dots as a Sustained Drug Delivery for Anticancer Therapy.姜黄素负载碳点的绿色合成作为抗癌治疗的持续药物递送
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