Division of General Internal Medicine, Department of Medicine, University of Minnesota, MMC 741. 420 Delaware St SE, Minneapolis, MN, 55455, USA.
Division of Hospital Pediatrics, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
J Gen Intern Med. 2017 Dec;32(12):1407-1409. doi: 10.1007/s11606-017-4111-1. Epub 2017 Jun 29.
Cannabis hyperemesis syndrome (CHS) is a condition in which some patients with long-term, frequent use of cannabis paradoxically develop recurrent episodes of nausea and vomiting. The pathophysiology underlying this condition is poorly understood, as is the explanation for its common association with patients' discovery that hot-water bathing alleviates symptoms. We describe the case of a 24-year-old male with daily marijuana use and a history of CHS who was found to have rhabdomyolysis induced by a period of 15 h of continuous jogging after he discovered that this activity helped to alleviate his symptoms. To our knowledge, this is the first reported case of exercise-alleviated CHS symptoms, and we propose that this case provides support to the theory of redistribution of enteric blood flow as the mechanism behind the learned hot-water bathing behavior seen so commonly in CHS.
大麻相关性恶心呕吐综合征（Cannabis hyperemesis syndrome，CHS）是一种病症，长期、频繁使用大麻的一些患者会出现反复恶心和呕吐。该病症的病理生理学机制尚未得到充分理解，同样不清楚的还有为什么该病症通常与患者发现热水浴可缓解症状相关联。我们描述了一名 24 岁男性的病例，他每日吸食大麻，患有 CHS，在发现连续慢跑 15 小时可以缓解症状后，出现横纹肌溶解。据我们所知，这是首例报道的运动缓解 CHS 症状的病例，我们提出，该病例支持这样一种理论，即肠道血流再分布是 CHS 中常见的热水浴行为背后的机制。
