[获取针对百日咳博德特氏菌抗原的单克隆抗体]
[Obtaining monoclonal antibodies to Bordetella pertussis antigens].
作者信息
Sviridov V V, Kozhevnikova E V
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1985 Sep(9):67-70.
PMID:2866646
Abstract
The immunization of mice with the protein fraction of B. pertussis strain 305 has made it possible to obtain hybridomas producing monoclonal antibodies to B. pertussis antigens. Ascitic fluids containing monoclonal antibodies react in the ELISA in high titers and actively agglutinate B. pertussis strains 305 and 475.
摘要
用百日咳杆菌305株的蛋白组分免疫小鼠，使得获得产生针对百日咳杆菌抗原的单克隆抗体的杂交瘤成为可能。含有单克隆抗体的腹水在酶联免疫吸附测定（ELISA）中以高滴度发生反应，并能有效地凝集百日咳杆菌305株和475株。
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