Lelliott P T, Monteiro W O
Drugs. 1986 Jan;31(1):75-80. doi: 10.2165/00003495-198631010-00006.
Obsessive-compulsive disorder (OCD) is an uncommon but difficult to manage problem. Behaviour therapy is the treatment of choice, with clomipramine as an adjunct in patients with coexisting depression. However, the incidence of side effects with the doses required (up to 200 mg daily, or occasionally higher) is high, and the side effects may be intolerable to some patients. Benzodiazepines have no effect on the core symptoms of OCD, and their usefulness as long term anxiolytics is outweighed by the risks of physical and psychological dependence. There is no place for antipsychotic drugs in managing obsessive-compulsive disorder.
强迫症（OCD）是一种不常见但难以处理的问题。行为疗法是首选治疗方法，氯米帕明可作为伴有抑郁症患者的辅助治疗药物。然而，所需剂量（每日高达200毫克，偶尔更高）的副作用发生率很高，且某些患者可能无法耐受这些副作用。苯二氮䓬类药物对强迫症的核心症状无效，其作为长期抗焦虑药的益处被身体和心理依赖的风险所抵消。抗精神病药物在治疗强迫症方面没有用。
