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The potential of gut microbiota and fecal volatile organic compounds analysis as early diagnostic biomarker for necrotizing enterocolitis and sepsis in preterm infants.肠道微生物群和粪便挥发性有机化合物分析作为早产儿坏死性小肠结肠炎和脓毒症早期诊断生物标志物的潜力。
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本文引用的文献

1
The Role of Mucosal Immunity in the Pathogenesis of Necrotizing Enterocolitis.黏膜免疫在坏死性小肠结肠炎发病机制中的作用
Front Pediatr. 2017 Mar 3;5:40. doi: 10.3389/fped.2017.00040. eCollection 2017.
2
Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis.早产儿坏死性小肠结肠炎发病前肠道菌群失调：系统评价和荟萃分析。
Microbiome. 2017 Mar 9;5(1):31. doi: 10.1186/s40168-017-0248-8.
3
Fecal Bile Salts and the Development of Necrotizing Enterocolitis in Preterm Infants.粪便胆汁盐与早产儿坏死性小肠结肠炎的发生
PLoS One. 2017 Jan 3;12(1):e0168633. doi: 10.1371/journal.pone.0168633. eCollection 2017.
4
Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease.早产儿肠道的细菌和代谢时间性发展揭示了健康和疾病中的特定特征。
Microbiome. 2016 Dec 29;4(1):67. doi: 10.1186/s40168-016-0216-8.
5
Polyunsaturated Fatty Acids and Their Derivatives: Therapeutic Value for Inflammatory, Functional Gastrointestinal Disorders, and Colorectal Cancer.多不饱和脂肪酸及其衍生物：对炎症性、功能性胃肠疾病和结直肠癌的治疗价值。
Front Pharmacol. 2016 Dec 1;7:459. doi: 10.3389/fphar.2016.00459. eCollection 2016.
6
Pathogenesis of NEC: Impact of an altered intestinal microbiome.坏死性小肠结肠炎的发病机制：肠道微生物群改变的影响
Semin Perinatol. 2017 Feb;41(1):29-35. doi: 10.1053/j.semperi.2016.09.015. Epub 2016 Dec 13.
7
Sniffing Out Paediatric Gastrointestinal Diseases: The Potential of Volatile Organic Compounds as Biomarkers for Disease.嗅出小儿胃肠疾病：挥发性有机化合物作为疾病生物标志物的潜力
J Pediatr Gastroenterol Nutr. 2016 Dec;63(6):585-591. doi: 10.1097/MPG.0000000000001250.
8
Acylcarnitine Profiles Reflect Metabolic Vulnerability for Necrotizing Enterocolitis in Newborns Born Premature.酰基肉碱谱反映早产新生儿坏死性小肠结肠炎的代谢易感性。
J Pediatr. 2017 Feb;181:80-85.e1. doi: 10.1016/j.jpeds.2016.10.019. Epub 2016 Nov 8.
9
Blood Level of Inter-Alpha Inhibitor Proteins Distinguishes Necrotizing Enterocolitis From Spontaneous Intestinal Perforation.α-间抑制蛋白的血液水平可区分坏死性小肠结肠炎与自发性肠穿孔。
J Pediatr. 2017 Jan;180:135-140.e1. doi: 10.1016/j.jpeds.2016.09.016. Epub 2016 Oct 10.
10
The human milk oligosaccharide 2'-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine.人乳寡糖2'-岩藻糖基乳糖通过增强新生儿肠道的肠系膜灌注来减轻实验性坏死性小肠结肠炎的严重程度。
Br J Nutr. 2016 Oct;116(7):1175-1187. doi: 10.1017/S0007114516002944. Epub 2016 Sep 9.

The Microbiome and Biomarkers for Necrotizing Enterocolitis: Are We Any Closer to Prediction?

作者信息

Rusconi Brigida, Good Misty, Warner Barbara B

机构信息

Division of Gastroenterology, Hepatology & Nutrition, Pathobiology Research Unit, Washington University School of Medicine, St Louis, MO; Department of Pediatrics, Washington University School of Medicine, St Louis, MO.

Department of Pediatrics, Washington University School of Medicine, St Louis, MO; Division of Newborn Medicine, Washington University School of Medicine, St Louis, MO.

出版信息

J Pediatr. 2017 Oct;189:40-47.e2. doi: 10.1016/j.jpeds.2017.05.075. Epub 2017 Jun 29.

DOI:10.1016/j.jpeds.2017.05.075
PMID:28669607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5614810/
Abstract
摘要