奥美沙坦相关小肠病
Olmesartan-associated enteropathy.
作者信息
Ebrahim Vivian S, Martin Jason, Murthy Stacey, Odstrcil Elizabeth, Huang He, Polter Daniel
机构信息
Division of Gastroenterology, Department of Internal Medicine (Ebrahim, Martin, Odstrcil, Polter) and the Department of Pathology (Murthy, Huang), Baylor University Medical Center, Dallas, Texas.
出版信息
Proc (Bayl Univ Med Cent). 2017 Jul;30(3):348-350. doi: 10.1080/08998280.2017.11929644.
Abstract
Olmesartan, an angiotensin-receptor blocker frequently prescribed for hypertension, has been commercially available since 2002. In 2012, olmesartan-associated enteropathy was described, and the Food and Drug Administration now requires a black-box warning for olmesartan regarding severe diarrhea. The disorder can be life-threatening and often requires hospitalization. We present three cases that represent different aspects of this disorder, as well as some unusual features.
摘要
奥美沙坦是一种常用于治疗高血压的血管紧张素受体阻滞剂，自2002年起已在市场上销售。2012年，有人描述了与奥美沙坦相关的肠病，美国食品药品监督管理局现在要求对奥美沙坦发出关于严重腹泻的黑框警告。这种疾病可能危及生命，通常需要住院治疗。我们介绍了三例代表这种疾病不同方面的病例，以及一些不寻常的特征。
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