Liu Qing, Wang Yongshun, van Heck Cornelis Hermanus, Qiao Wei
Department of Nuclear Medicine and Medical PET Center, The Second Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou.
School of Physical Education and Sport, Huaqiao University, Xiamen, People's Republic of China.
Neuropsychiatr Dis Treat. 2017 Jun 16;13:1597-1602. doi: 10.2147/NDT.S132001. eCollection 2017.
Hormone level fluctuation across the menstrual cycle causes women to experience negative emotions and also affects their mood regulation and stress sensitivity. However, the stress reactivity and emotional variations in women with premenstrual syndrome (PMS), who are especially sensitive to the variations in hormone cycles, have not been explained.
The present study used an electroencephalogram (EEG) stress evaluation test, a physiology stress evaluation test, and the positive affect and negative affect scale (PANAS) to evaluate the stress reactivity pattern and emotional state of women with PMS.
The results showed that women with PMS had higher negative affect and lower positive affect compared with controls. Moreover, under stressful conditions, the women with PMS had a higher alpha activity and a lower respiration rate than the controls. The differences in stress reactivity and emotional states between women with PMS and controls were based on a covariant analysis with menstrual cycle (luteal and follicular phases) as the covariate.
The results demonstrated that, compared with controls, women suffering from PMS have a continuous abnormality in emotional state and stress reactivity, which was independent of the menstrual cycle.
月经周期中激素水平的波动会导致女性出现负面情绪，还会影响她们的情绪调节和应激敏感性。然而，经前综合征（PMS）女性对激素周期变化尤为敏感，其应激反应性和情绪变化尚未得到解释。
本研究采用脑电图（EEG）应激评估测试、生理应激评估测试以及正负性情绪量表（PANAS）来评估PMS女性的应激反应模式和情绪状态。
结果显示，与对照组相比，PMS女性的负性情绪更高，正性情绪更低。此外，在应激条件下，PMS女性比对照组具有更高的α波活动和更低的呼吸频率。PMS女性与对照组在应激反应性和情绪状态上的差异基于以月经周期（黄体期和卵泡期）为协变量的协方差分析。
结果表明，与对照组相比，患有PMS的女性在情绪状态和应激反应性方面存在持续异常，且与月经周期无关。
