在波兰圈养马匹的圆线科种群中寻找伊维菌素耐药性。
Searching for ivermectin resistance in a Strongylidae population of horses stabled in Poland.
作者信息
Zak A, Siwinska N, Slowikowska M, Borowicz H, Kubiak K, Hildebrand J, Popiolek M, Niedzwiedz A
机构信息
Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366, Wroclaw, Poland.
Department of Parasitology, Institute of Genetics and Microbiology, University of Wroclaw, ul. S. Przybyszewskiego 63/77, 51-148, Wroclaw, Poland.
出版信息
BMC Vet Res. 2017 Jul 3;13(1):210. doi: 10.1186/s12917-017-1133-1.
BACKGROUND
There are no available studies describing the possible resistance of strongyles to ivermectin in horses in Poland. One hundred seventy three horses from nine stud farms from South-Western Poland were studied. The effectiveness of ivermectin was studied on the 14th day after ivermectin administration using the fecal egg count reduction test, and a long-term observation of the egg reappearance period was carried out. The fecal study was carried out using a modified McMaster method, which typically detects 20 eggs per gram of stool. The results were subjected to statistical analysis that enabled quantification of the eggs in the stool samples.
RESULTS
The study revealed high efficacy of ivermectin on the 14th day after administration without a shortening of the egg reappearance period.
CONCLUSION
The results indicate that strongyles resistance to ivermectin in Poland is not a serious problem.
背景
目前尚无关于波兰马匹体内圆线虫对伊维菌素可能产生耐药性的研究。对来自波兰西南部9个种马场的173匹马进行了研究。在给予伊维菌素14天后，采用粪便虫卵计数减少试验研究伊维菌素的有效性，并对虫卵再现期进行了长期观察。粪便研究采用改良麦克马斯特法进行，该方法通常每克粪便可检测到20个虫卵。对结果进行了统计分析，从而能够对粪便样本中的虫卵进行定量。
结果
研究显示，给药14天后伊维菌素疗效显著，且虫卵再现期未缩短。
结论
结果表明，在波兰，圆线虫对伊维菌素的耐药性并非严重问题。
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