Elramalli Asma, Almshawt Nariman, Ahmed Mohamed Omar
Tripoli Medical Centre, Tripoli, Libya.
Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Libya.
Pan Afr Med J. 2017 Mar 29;26:180. doi: 10.11604/pamj.2017.26.180.9637. eCollection 2017.
A collection of 94 Gram-negative bacteria isolates, showing different antimicrobial resistance phenotypes including to the carbapenem classes was investigated. Strains were originated form clinical sources from a single hospital in Tripoli, Libya during 2015 and were identified based on cultural and phenotypic characteristics, and fully characterized by the VITEK automated system. Forty-eight percent (48%) of the collection was identified as Acinetobacter baumannii, 50% Klebsiella pneumoniae and 2% Escherichia coli. Resistance to the carbapenem classes was reported in 96% of the A. baumannii strains and 94% of the K. pneumonia strains. Seventy-eight percent (78%) of the isolates showed different multidrug-resistant (MDR) phenotypes, of which K. pneumoniae expressing the highest rates of MDRs(i.e. 91%). Emergence of resistance to carbapenems in the Gram-negative bacteria is a challenging global problem, particularly for Africa. Surveillance of these pathogens and appropriate actions are urgently required in Libyan healthcare settings.
对94株革兰氏阴性菌分离株进行了研究，这些分离株表现出不同的抗菌耐药表型，包括对碳青霉烯类药物的耐药性。这些菌株于2015年来自利比亚的黎波里一家医院的临床样本，根据培养和表型特征进行鉴定，并通过VITEK自动化系统进行全面表征。该样本中48%被鉴定为鲍曼不动杆菌，50%为肺炎克雷伯菌，2%为大肠杆菌。96%的鲍曼不动杆菌菌株和94%的肺炎克雷伯菌菌株对碳青霉烯类药物耐药。78%的分离株表现出不同的多重耐药（MDR）表型，其中肺炎克雷伯菌的多重耐药率最高（即91%）。革兰氏阴性菌对碳青霉烯类药物耐药性的出现是一个具有挑战性的全球性问题，对非洲而言尤为如此。利比亚的医疗环境迫切需要对这些病原体进行监测并采取适当行动。
