Farzanehfar Parisa, Horne Malcolm
a Florey Institute of Neurosciences and Mental Health , University of Melbourne , Parkville , Australia.
Expert Rev Med Devices. 2017 Aug;14(8):583-591. doi: 10.1080/17434440.2017.1349608. Epub 2017 Jul 6.
While objective measurement is routine in clinical care of most conditions, this has not been the case for Parkinson's Disease. Recent innovations make objective measurement in Parkinson's Disease possible and its utility and how this should be assessed is discussed here. Areas covered: Whilst therapies are effective in Parkinson's Disease, symptoms fluctuate in relation to treatment over the course of the day. Objective measurement makes it possible to assess symptom control, whether treatment is required and whether it achieved control. Objective measurement makes it possible to consider targets for therapeutic control and to begin an assessment of the value of improved control. Evidence for the effect of improved measurement on outcomes is only beginning to emerge. As symptom severity relates to quality of life and costs, reducing clinical scores and fluctuations through objective measurement is in the interest of both the patient and the health system. Expert commentary: In broad terms objective measurement should be used to identify patients whose symptoms lie outside the target range and then to assess whether therapy was effective in bringing them into control. While this is relevant to all stages of Parkinson's Disease specific clinical situations where this had greatest impact are discussed.
虽然客观测量在大多数疾病的临床护理中已成为常规操作，但帕金森病并非如此。最近的创新使得帕金森病的客观测量成为可能，本文将讨论其效用以及应如何进行评估。涵盖领域：虽然治疗方法对帕金森病有效，但症状在一天中会随着治疗而波动。客观测量使得评估症状控制情况、是否需要治疗以及治疗是否实现控制成为可能。客观测量使得能够考虑治疗控制的目标，并开始评估改善控制的价值。关于改进测量对结果影响的证据才刚刚开始出现。由于症状严重程度与生活质量和成本相关，通过客观测量降低临床评分和波动符合患者和卫生系统的利益。专家评论：从广义上讲，客观测量应用于识别症状超出目标范围的患者，然后评估治疗是否有效地将其控制住。虽然这与帕金森病的所有阶段都相关，但本文将讨论这种方法产生最大影响的具体临床情况。
