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患有同种免疫性血小板减少症的胎儿及新生儿的影像学检查与管理

Imaging and management of fetuses and neonates with alloimmune thrombocytopenia.

作者信息

Kovanlikaya Arzu, Tiwari Priyanka, Bussel James B

机构信息

Division of Pediatric Radiology, Department of Radiology, New York Presbyterian Hospital/Weill Cornell Medical College, New York, New York.

Division of Newborn Medicine, Department of Pediatrics, New York Presbyterian Hospital/Weill Cornell Medical College, New York, New York.

出版信息

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26690. Epub 2017 Jul 4.

DOI:10.1002/pbc.26690
PMID:28675682
Abstract

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the most common cause of severe neonatal thrombocytopenia and intracranial bleeding in term newborns. Intracranial hemorrhage (ICH) commonly results in death or severe, lasting neurologic disability. The timing of ICH is also important for management of the next affected pregnancy in cases of FNAIT. This manuscript reviews the advantages and disadvantages of the different radiologic methodologies to identify and characterize ICH. It discusses the limits of ultrasound and the advantages of magnetic resonance imaging allowing avoidance of the radiation associated with computed tomography (CT) scans.

摘要

胎儿和新生儿同种免疫性血小板减少症(FNAIT)是足月儿严重新生儿血小板减少症和颅内出血的最常见原因。颅内出血(ICH)通常会导致死亡或严重的、持久性神经功能障碍。对于FNAIT病例,ICH的发生时间对于下一受影响妊娠的管理也很重要。本文综述了不同影像学方法用于识别和表征ICH的优缺点。讨论了超声的局限性以及磁共振成像的优势,后者可避免与计算机断层扫描(CT)相关的辐射。

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