• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Epithelial-mesenchymal transition in cancer.癌症中的上皮-间质转化
Mol Oncol. 2017 Jul;11(7):715-717. doi: 10.1002/1878-0261.12094.
2
Growth factors in induction of epithelial-mesenchymal transition and metastasis.生长因子在诱导上皮-间充质转化和转移中的作用。
Cells Tissues Organs. 2011;193(1-2):85-97. doi: 10.1159/000320360. Epub 2010 Nov 3.
3
The role of interferon as a modifier of epithelial-mesenchymal transition in tumor cells.干扰素作为肿瘤细胞上皮-间质转化调节剂的作用。
Exp Oncol. 2011 Sep;33(3):178-81.
4
Bone marrow-derived CD11b+Jagged2+ cells promote epithelial-to-mesenchymal transition and metastasization in colorectal cancer.骨髓源 CD11b+Jagged2+ 细胞促进结直肠癌的上皮间质转化和转移。
Cancer Res. 2013 Jul 15;73(14):4233-46. doi: 10.1158/0008-5472.CAN-13-0085. Epub 2013 May 30.
5
Insights into cancer metastasis from a clinicopathologic perspective: Epithelial-Mesenchymal Transition is not a necessary step.从临床病理角度深入了解癌症转移:上皮-间充质转化不是必需步骤。
Int J Cancer. 2013 Apr 1;132(7):1487-95. doi: 10.1002/ijc.27745. Epub 2012 Sep 28.
6
Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin α6β4 and Notch1/Jagged2 signaling pathway.半乳糖凝集素-1 通过增强整合素 α6β4 和 Notch1/Jagged2 信号通路促进肺癌肿瘤转移。
Carcinogenesis. 2013 Jun;34(6):1370-81. doi: 10.1093/carcin/bgt040. Epub 2013 Feb 6.
7
Epithelial-to-mesenchymal transition leads to disease-stage differences in circulating tumor cell detection and metastasis in pre-clinical models of prostate cancer.上皮-间质转化导致前列腺癌临床前模型中循环肿瘤细胞检测和转移的疾病阶段差异。
Oncotarget. 2016 Nov 15;7(46):76125-76139. doi: 10.18632/oncotarget.12682.
8
MicroRNAs regulate the epithelial-mesenchymal transition and influence breast cancer invasion and metastasis.微小RNA调控上皮-间质转化并影响乳腺癌的侵袭和转移。
Tumour Biol. 2017 Feb;39(2):1010428317691682. doi: 10.1177/1010428317691682.
9
Diverse pathways of epithelial mesenchymal transition related with cancer progression and metastasis and potential effects of endocrine disrupting chemicals on epithelial mesenchymal transition process.上皮间质转化的多种途径与癌症的进展和转移有关,以及内分泌干扰物对上皮间质转化过程的潜在影响。
Mol Cell Endocrinol. 2017 Dec 5;457:103-113. doi: 10.1016/j.mce.2016.12.026. Epub 2016 Dec 29.
10
Cancer stemness and metastatic potential of the novel tumor cell line K3: an inner mutated cell of bone marrow-derived mesenchymal stem cells.新型肿瘤细胞系K3的癌干性和转移潜能:一种骨髓来源间充质干细胞的内部突变细胞
Oncotarget. 2017 Jun 13;8(24):39522-39533. doi: 10.18632/oncotarget.17133.

引用本文的文献

1
The Role of Iron Chelation Therapy in Colorectal Cancer: A Systematic Review on Its Mechanisms and Therapeutic Potential.铁螯合疗法在结直肠癌中的作用:关于其机制和治疗潜力的系统评价
Cancer Med. 2025 Jul;14(13):e71019. doi: 10.1002/cam4.71019.
2
Unraveling the chemotherapeutic potential of taxifolin ruthenium-p-cymene complex in breast carcinoma: Insights into AhR signaling pathway in vitro and in vivo.揭示紫杉叶素钌-对异丙基苯配合物在乳腺癌中的化疗潜力:对体外和体内芳烃受体信号通路的见解。
Transl Oncol. 2024 Nov;49:102107. doi: 10.1016/j.tranon.2024.102107. Epub 2024 Aug 23.
3
A Multi-Omics Analysis of an Exhausted T Cells' Molecular Signature in Pan-Cancer.泛癌中耗竭性T细胞分子特征的多组学分析
J Pers Med. 2024 Jul 18;14(7):765. doi: 10.3390/jpm14070765.
4
The immune regulation and therapeutic potential of the SMAD gene family in breast cancer.SMAD 基因家族在乳腺癌中的免疫调节和治疗潜力。
Sci Rep. 2024 Mar 21;14(1):6769. doi: 10.1038/s41598-024-57189-6.
5
The emerging role of breast cancer derived extracellular vesicles-mediated intercellular communication in ovarian cancer progression and metastasis.乳腺癌衍生细胞外囊泡介导的细胞间通讯在卵巢癌进展和转移中的新作用。
Med Oncol. 2023 Dec 26;41(1):30. doi: 10.1007/s12032-023-02285-2.
6
NCK1-AS1 promotes the proliferation, migration, invasion, and EMT of non-small cell lung cancer by regulating the miR-361-5p/ADAM10 axis.NCK1-AS1通过调控miR-361-5p/ADAM10轴促进非小细胞肺癌的增殖、迁移、侵袭和上皮-间质转化。
Histol Histopathol. 2023 Dec;38(12):1453-1464. doi: 10.14670/HH-18-604. Epub 2023 Mar 3.
7
Acquired radioresistance in EMT6 mouse mammary carcinoma cell line is mediated by CTLA-4 and PD-1 through JAK/STAT/PI3K pathway.EMT6 鼠乳腺肿瘤细胞系获得性放射抵抗是由 CTLA-4 和 PD-1 通过 JAK/STAT/PI3K 通路介导的。
Sci Rep. 2023 Feb 22;13(1):3108. doi: 10.1038/s41598-023-29925-x.
8
Osteopontin and Cancer: Insights into Its Role in Drug Resistance.骨桥蛋白与癌症:对其在耐药性中作用的见解
Biomedicines. 2023 Jan 12;11(1):197. doi: 10.3390/biomedicines11010197.
9
HLA-BAT1 alters migration, invasion and pro-inflammatory cytokines in prostate cancer.人类白细胞抗原B关联转录本1(HLA - BAT1)改变前列腺癌中的迁移、侵袭和促炎细胞因子。
Front Oncol. 2022 Nov 23;12:969396. doi: 10.3389/fonc.2022.969396. eCollection 2022.
10
Essential role of aerobic glycolysis in epithelial-to-mesenchymal transition during carcinogenesis.有氧糖酵解在致癌过程中上皮-间质转化中的重要作用。
Clin Transl Oncol. 2022 Oct;24(10):1844-1855. doi: 10.1007/s12094-022-02851-6. Epub 2022 Jun 25.

本文引用的文献

1
A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes.连续的 EMT-MET 机制驱动人胚胎干细胞向肝细胞分化。
Nat Commun. 2017 May 3;8:15166. doi: 10.1038/ncomms15166.
2
TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition.TGF-β 家族信号在上皮分化和上皮-间充质转化中的作用。
Cold Spring Harb Perspect Biol. 2018 Jan 2;10(1):a022194. doi: 10.1101/cshperspect.a022194.
3
Emerging Biological Principles of Metastasis.转移的新兴生物学原理
Cell. 2017 Feb 9;168(4):670-691. doi: 10.1016/j.cell.2016.11.037.
4
EMT: 2016.EMT:2016 年。
Cell. 2016 Jun 30;166(1):21-45. doi: 10.1016/j.cell.2016.06.028.
5
Stability of the hybrid epithelial/mesenchymal phenotype.上皮/间充质混合表型的稳定性
Oncotarget. 2016 May 10;7(19):27067-84. doi: 10.18632/oncotarget.8166.
6
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.上皮-间质转化并非肺转移所必需,但会导致化疗耐药。
Nature. 2015 Nov 26;527(7579):472-6. doi: 10.1038/nature15748. Epub 2015 Nov 11.
7
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.上皮-间质转化对胰腺癌转移并非必需,但可诱导其产生化疗耐药性。
Nature. 2015 Nov 26;527(7579):525-530. doi: 10.1038/nature16064. Epub 2015 Nov 11.
8
F-box proteins: Keeping the epithelial-to-mesenchymal transition (EMT) in check.F-box蛋白:控制上皮-间质转化(EMT)
Semin Cancer Biol. 2016 Feb;36:71-9. doi: 10.1016/j.semcancer.2015.10.003. Epub 2015 Nov 11.
9
Rethinking differentiation: stem cells, regeneration, and plasticity.重新思考分化:干细胞、再生和可塑性。
Cell. 2014 Mar 27;157(1):110-9. doi: 10.1016/j.cell.2014.02.041.
10
Molecular mechanisms of epithelial-mesenchymal transition.上皮-间质转化的分子机制。
Nat Rev Mol Cell Biol. 2014 Mar;15(3):178-96. doi: 10.1038/nrm3758.

Epithelial-mesenchymal transition in cancer.

作者信息

Moustakas Aristidis, de Herreros Antonio Garcia

机构信息

Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Biomedical Center, Ludwig Institute for Cancer Research, Uppsala University, Sweden.

Cancer Research Program, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain.

出版信息

Mol Oncol. 2017 Jul;11(7):715-717. doi: 10.1002/1878-0261.12094.

DOI:10.1002/1878-0261.12094
PMID:28677253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5496492/
Abstract
摘要