Epithelial-mesenchymal transition in cancer.
作者信息
Moustakas Aristidis, de Herreros Antonio Garcia
机构信息
Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Biomedical Center, Ludwig Institute for Cancer Research, Uppsala University, Sweden.
Cancer Research Program, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain.
出版信息
Mol Oncol. 2017 Jul;11(7):715-717. doi: 10.1002/1878-0261.12094.
Abstract
摘要
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本文引用的文献
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A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes.连续的 EMT-MET 机制驱动人胚胎干细胞向肝细胞分化。
Nat Commun. 2017 May 3;8:15166. doi: 10.1038/ncomms15166.
2
TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition.TGF-β 家族信号在上皮分化和上皮-间充质转化中的作用。
Cold Spring Harb Perspect Biol. 2018 Jan 2;10(1):a022194. doi: 10.1101/cshperspect.a022194.
3
Emerging Biological Principles of Metastasis.转移的新兴生物学原理
Cell. 2017 Feb 9;168(4):670-691. doi: 10.1016/j.cell.2016.11.037.
4
EMT: 2016.EMT：2016 年。
Cell. 2016 Jun 30;166(1):21-45. doi: 10.1016/j.cell.2016.06.028.
5
Stability of the hybrid epithelial/mesenchymal phenotype.上皮/间充质混合表型的稳定性
Oncotarget. 2016 May 10;7(19):27067-84. doi: 10.18632/oncotarget.8166.
6
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.上皮-间质转化并非肺转移所必需，但会导致化疗耐药。
Nature. 2015 Nov 26;527(7579):472-6. doi: 10.1038/nature15748. Epub 2015 Nov 11.
7
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.上皮-间质转化对胰腺癌转移并非必需，但可诱导其产生化疗耐药性。
Nature. 2015 Nov 26;527(7579):525-530. doi: 10.1038/nature16064. Epub 2015 Nov 11.
8
F-box proteins: Keeping the epithelial-to-mesenchymal transition (EMT) in check.F-box蛋白：控制上皮-间质转化（EMT）
Semin Cancer Biol. 2016 Feb;36:71-9. doi: 10.1016/j.semcancer.2015.10.003. Epub 2015 Nov 11.
9
Rethinking differentiation: stem cells, regeneration, and plasticity.重新思考分化：干细胞、再生和可塑性。
Cell. 2014 Mar 27;157(1):110-9. doi: 10.1016/j.cell.2014.02.041.
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Molecular mechanisms of epithelial-mesenchymal transition.上皮-间质转化的分子机制。
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