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澳大利亚急诊科偏头痛的就诊与处方模式:一项描述性探索性研究。

The presenting and prescribing patterns of migraine in an Australian emergency department: A descriptive exploratory study.

作者信息

Shao Emily, Hughes James, Eley Rob

机构信息

Royal Brisbane and Women's Hospital, Brisbane, Australia.

Emergency Department, Princess Alexandra Hospital, Brisbane, Australia.

出版信息

World J Emerg Med. 2017;8(3):170-176. doi: 10.5847/wjem.j.1920-8642.2017.03.002.

Abstract

BACKGROUND

Migraine is a common neurological condition that frequently presents to the emergency department (ED). Many medications are available to treat migraine. This study aims to characterize the demographics of patients who present to a large metropolitan ED with migraine, and to identify the medications used in treating this condition.

METHODS

This study is a retrospective database interrogation of clinical records, used to collect quantitative data on patient demographics and medication prescriptions in the ED.

RESULTS

A total of 2 228 patients were identified as being treated for migraine over a 10-year period. The proportion of the ED population presenting with migraine steadily increased in this time. Females (71%) more commonly presented to the ED with migraine than males. The migraine population was significantly younger (=37.05, =13.23) than the whole ED population (=46.17 =20.50) (<0.001). A variety of medications were used in the treatment of migraine in the ED. Simple analgesics such as paracetamol and ibuprofen, anti-emetics and intravenous (IV) fluids with phenothiazine additives were commonly used. Over 20% of patients were prescribed oral or parenteral opiates (42 of 194 initial medication prescriptions, and 64 of 292 as required medication prescriptions). Triptans were very rarely used.

CONCLUSION

Migraine is an increasingly common presentation to the ED. People presenting to the ED with migraine are more likely to be younger and female than the general ED population. Peak presentations for migraines occurred in January and February. The medications that are prescribed in the ED for migraine is varied and are not always in line with current evidence for the treatment of migraine. The excessive reliance on opiates and lack of the use of triptans denotes a significant variation from published guidelines.

摘要

背景

偏头痛是一种常见的神经系统疾病,经常出现在急诊科(ED)。有许多药物可用于治疗偏头痛。本研究旨在描述到大都市急诊科就诊的偏头痛患者的人口统计学特征,并确定用于治疗该疾病的药物。

方法

本研究是对临床记录进行回顾性数据库查询,用于收集急诊科患者人口统计学和药物处方的定量数据。

结果

在10年期间,共确定2228例患者因偏头痛接受治疗。在此期间,急诊科中偏头痛患者的比例稳步上升。女性(71%)比男性更常因偏头痛到急诊科就诊。偏头痛患者群体(平均年龄=37.05岁,标准差=13.23岁)比整个急诊科患者群体(平均年龄=46.17岁,标准差=20.50岁)显著年轻(P<0.001)。急诊科使用了多种药物治疗偏头痛。常用的简单镇痛药如对乙酰氨基酚和布洛芬、止吐药以及含有吩噻嗪添加剂的静脉输液。超过20%的患者被开具口服或胃肠外阿片类药物(194份初始药物处方中有42份,按需药物处方中有292份中的64份)。曲坦类药物很少使用。

结论

偏头痛在急诊科的就诊越来越普遍。与普通急诊科患者相比,因偏头痛到急诊科就诊的人更可能年轻且为女性。偏头痛就诊高峰出现在1月和2月。急诊科用于治疗偏头痛的药物种类繁多,并不总是与当前偏头痛治疗证据一致。对阿片类药物的过度依赖以及曲坦类药物的缺乏使用表明与已发表的指南存在显著差异。

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