重型β地中海贫血脾切除患者的巨细胞病毒感染：免疫功能正常还是免疫抑制？
Cytomegalovirus infection in a splenectomized with -thalassemia major: immunocompetent or immunosuppressed?
作者信息
Liatsos George D, Pirounaki Maria, Lazareva Angelina, Kikezou Georgia, Dourakis Spyridon P
机构信息
nd2nd Academic Department of Internal Medicine Medical School Hippokratio General Hospital National and Kapodistrian Athens University Athens Greece.
出版信息
Clin Case Rep. 2017 May 16;5(7):1063-1066. doi: 10.1002/ccr3.1001. eCollection 2017 Jul.
Abstract
We should possibly revise our knowledge about risk assessment of splenectomized individuals with -thalassemia major. Besides their known risk of certain bacterial infection, they might be also in a risk of life-threatening primary cytomegalovirus (CMV) infection and end-, multi-organ disease, in the context of their immunosuppression status. Prompt and appropriate treatment initiation can be life saving.
摘要
我们或许应该修正对重型β地中海贫血脾切除患者风险评估的认识。除了已知的某些细菌感染风险外，鉴于其免疫抑制状态，他们还可能面临危及生命的原发性巨细胞病毒（CMV）感染以及终末期多器官疾病的风险。及时且恰当的治疗启动可能挽救生命。
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