与吸食合成大麻素相关的双侧肾皮质坏死。

Bilateral renal cortical necrosis associated with smoking synthetic cannabinoids.

作者信息

Mansoor Kanaan, Zawodniak Ashley, Nadasdy Tibor, Khitan Zeid J

机构信息

Kanaan Mansoor, Ashley Zawodniak, Zeid J Khitan, Internal Medicine Department, Joan C Edwards School of Medicine, Marshall University, Huntington, WV 25701, United States.

出版信息

World J Clin Cases. 2017 Jun 16;5(6):234-237. doi: 10.12998/wjcc.v5.i6.234.

DOI:10.12998/wjcc.v5.i6.234

PMID:28685136

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5480071/

Abstract

Synthetic cannabinoids have become a common drug of abuse in recent years and their toxicities have come to light as well. They are known to be notorious for the kidneys, with acute tubular necrosis, acute interstitial nephritis and rhabdomyolysis induced renal injury being the frequent nephrotoxic outcomes in users. We report a case of bilateral renal cortical necrosis, leading to irreversible renal damage and lifelong dialysis dependency.

摘要

近年来，合成大麻素已成为一种常见的滥用药物，其毒性也已暴露出来。众所周知，它们对肾脏危害极大，急性肾小管坏死、急性间质性肾炎和横纹肌溶解引起的肾损伤是使用者常见的肾毒性后果。我们报告一例双侧肾皮质坏死病例，导致不可逆转的肾损伤和终身依赖透析。