Kalokhoran Ali Yousefzadeh, Ghalyanchilangeroudi Arash, Hosseini Hossein, Madadgar Omid, Karimi Vahid, Hashemzadeh Masoud, Hesari Parvaneh, Zabihi Petroudi Mohammad Taha, Najafi Hamideh
Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Department of Clinical Sciences, Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Alborz, Iran.
Arch Virol. 2017 Oct;162(10):3183-3189. doi: 10.1007/s00705-017-3473-3. Epub 2017 Jul 8.
Avian infectious bronchitis (IB) is an acute and highly contagious viral disease causing severe economic losses in the poultry industry. The 793/B IB virus is an important infectious bronchitis virus (IBV) genotype currently circulating in several countries, including Iran. One hundred confirmed IBV samples (between 2014 and 2015; from 15 provinces in Iran) were selected for genotyping based on S1 sequencing. After phylogenetic analysis, it was found that 30% of the IBV isolates belonged to the 793/B genotype. Results showed that the Iranian 793/B-like IBV isolates could be divided in to three clusters: 4/91-like (50%), 1/96-like (40%), and IB88-like (10%). The sequence similarity between Iranian 793/B-like IBV isolates is 87.69%-100%. The highest identity is between the 4/91 and IB88 clusters (96.38%), and the lowest similarity is between the 1/96 and IB88 clusters (87.62%). This study provides a comprehensive analysis of 793/B-type IBV in Iran and characterization of IBV molecular epidemiology in the country.
禽传染性支气管炎（IB）是一种急性且高度传染性的病毒性疾病，给家禽业造成严重经济损失。793/B型传染性支气管炎病毒是一种重要的传染性支气管炎病毒（IBV）基因型，目前在包括伊朗在内的几个国家流行。基于S1测序，选择了100份确诊的IBV样本（2014年至2015年期间；来自伊朗15个省份）进行基因分型。经过系统发育分析，发现30%的IBV分离株属于793/B基因型。结果表明，伊朗的793/B样IBV分离株可分为三个簇：4/91样（50%）、1/96样（40%）和IB88样（10%）。伊朗793/B样IBV分离株之间的序列相似性为87.69%-100%。4/91和IB88簇之间的同一性最高（96.38%），1/96和IB88簇之间的相似性最低（87.62%）。本研究对伊朗的793/B型IBV进行了全面分析，并对该国IBV分子流行病学进行了特征描述。
