Suppr超能文献

相似文献

1
Discovery of a Covalent Kinase Inhibitor from a DNA-Encoded Small-Molecule Library × Protein Library Selection.
J Am Chem Soc. 2017 Aug 2;139(30):10192-10195. doi: 10.1021/jacs.7b04880. Epub 2017 Jul 20.
3
Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry.
Bioorg Med Chem. 2021 Jul 15;42:116223. doi: 10.1016/j.bmc.2021.116223. Epub 2021 May 19.
4
Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads.
J Am Chem Soc. 2025 May 7;147(18):15469-15481. doi: 10.1021/jacs.5c01712. Epub 2025 Apr 28.
5
Design, synthesis and selection of DNA-encoded small-molecule libraries.
Nat Chem Biol. 2009 Sep;5(9):647-54. doi: 10.1038/nchembio.211. Epub 2009 Aug 2.
6
Twenty-five Years of DNA-Encoded Chemical Libraries.
Chembiochem. 2017 May 4;18(9):827-828. doi: 10.1002/cbic.201700130. Epub 2017 Mar 20.
9
Protocols for the Design of Kinase-focused Compound Libraries.
Mol Inform. 2018 May;37(5):e1700119. doi: 10.1002/minf.201700119. Epub 2017 Nov 8.
10
Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer.
Bioorg Med Chem. 2021 Sep 1;45:116324. doi: 10.1016/j.bmc.2021.116324. Epub 2021 Jul 22.

引用本文的文献

1
Identification of Structurally Novel KRAS Inhibitors through Covalent DNA-Encoded Library Screening.
J Med Chem. 2025 Feb 27;68(4):4801-4817. doi: 10.1021/acs.jmedchem.4c03071. Epub 2025 Feb 11.
2
Encoding and display technologies for combinatorial libraries in drug discovery: The coming of age from biology to therapy.
Acta Pharm Sin B. 2024 Aug;14(8):3362-3384. doi: 10.1016/j.apsb.2024.04.006. Epub 2024 Apr 10.
3
Recording Binding Information Directly into DNA-Encoded Libraries Using Terminal Deoxynucleotidyl Transferase.
J Am Chem Soc. 2023 Sep 27;145(38):20874-20882. doi: 10.1021/jacs.3c05961. Epub 2023 Sep 13.
4
Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries.
ACS Omega. 2023 Jul 6;8(28):25090-25100. doi: 10.1021/acsomega.3c01775. eCollection 2023 Jul 18.
5
Small-molecule discovery through DNA-encoded libraries.
Nat Rev Drug Discov. 2023 Sep;22(9):699-722. doi: 10.1038/s41573-023-00713-6. Epub 2023 Jun 16.
6
Machine-Learning-Based Data Analysis Method for Cell-Based Selection of DNA-Encoded Libraries.
ACS Omega. 2023 May 15;8(21):19057-19071. doi: 10.1021/acsomega.3c02152. eCollection 2023 May 30.
7
Integrated Covalent Drug Design Workflow Using Site Identification by Ligand Competitive Saturation.
J Chem Theory Comput. 2023 May 23;19(10):3007-3021. doi: 10.1021/acs.jctc.3c00232. Epub 2023 Apr 28.
8
Ethacrynic Acid: A Promising Candidate for Drug Repurposing as an Anticancer Agent.
Int J Mol Sci. 2023 Apr 4;24(7):6712. doi: 10.3390/ijms24076712.
9
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins.
ACS Med Chem Lett. 2022 Aug 15;13(10):1574-1581. doi: 10.1021/acsmedchemlett.2c00127. eCollection 2022 Oct 13.
10
The protein kinase CK1: Inhibition, activation, and possible allosteric modulation.
Front Mol Biosci. 2022 Aug 24;9:916232. doi: 10.3389/fmolb.2022.916232. eCollection 2022.

本文引用的文献

1
Design, preparation, and selection of DNA-encoded dynamic libraries.
Chem Sci. 2015 Dec 1;6(12):7097-7104. doi: 10.1039/c5sc02467f. Epub 2015 Sep 11.
2
DNA-encoded chemistry: enabling the deeper sampling of chemical space.
Nat Rev Drug Discov. 2017 Feb;16(2):131-147. doi: 10.1038/nrd.2016.213. Epub 2016 Dec 9.
3
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.
Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):E7880-E7889. doi: 10.1073/pnas.1610978113. Epub 2016 Nov 18.
4
DNA-encoded chemical libraries: foundations and applications in lead discovery.
Drug Discov Today. 2016 Nov;21(11):1828-1834. doi: 10.1016/j.drudis.2016.07.013. Epub 2016 Jul 28.
5
Proteome-wide covalent ligand discovery in native biological systems.
Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
6
Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening.
ACS Comb Sci. 2016 Jun 13;18(6):320-9. doi: 10.1021/acscombsci.5b00194. Epub 2016 May 3.
7
Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination.
Biol Reprod. 2016 May;94(5):103. doi: 10.1095/biolreprod.115.138057. Epub 2016 Mar 23.
8
Chemical Biology Probes from Advanced DNA-encoded Libraries.
ACS Chem Biol. 2016 Feb 19;11(2):296-307. doi: 10.1021/acschembio.5b00981. Epub 2016 Jan 28.
10
Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules.
Angew Chem Int Ed Engl. 2015 May 11;54(20):6057-61. doi: 10.1002/anie.201412276. Epub 2015 Mar 13.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验