Tuk Jacco G C, van Wijk Arjen J, Mertens Ine C, Keleş Zühal, Lindeboom Jérôme A H, Milstein Dan M J
Department of Oral & Maxillofacial Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Oral & Maxillofacial Surgery, Amstelland Hospital, Amstelveen, The Netherlands.
Department of Oral Health Sciences, Social Dentistry Division, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Sep;124(3):240-247. doi: 10.1016/j.oooo.2017.04.017. Epub 2017 May 4.
The aim of this study was to evaluate the analgesic effects of low-level laser therapy (LLLT) on preinjection sites in patients scheduled for third molar removal.
This double-blind randomized controlled trial included 163 healthy patients undergoing third molar extractions. The study participants were randomly divided into an LLLT and a placebo group. Objective and subjective data sets were obtained from physiologic feedback (heart rate and sweat response) and a questionnaire, respectively. In the LLLT group, each targeted injection site was irradiated twice with 198 mW continuous wave for 30 seconds with a 0.088 cm focal spot at an applied energy of 5.94 J and fluence of 67.50 J/cm. Measurements were recorded from 4 time-points during data acquisition.
There was no significant difference between the LLLT and placebo groups in pain experience scores associated with the injected sites for maxillary or mandibular third molar extractions. Mean heart rates before and during injection were lower in the LLLT group than in the placebo group for both maxillary and mandibular regions. No statistically significant differences were observed for any remaining parameters.
The present data indicated that preinjection LLLT did not effectively decrease the pain felt during local anesthetic injections before third molar surgery.
本研究旨在评估低强度激光疗法（LLLT）对计划拔除第三磨牙患者注射前部位的镇痛效果。
这项双盲随机对照试验纳入了163例接受第三磨牙拔除术的健康患者。研究参与者被随机分为LLLT组和安慰剂组。客观和主观数据集分别从生理反馈（心率和出汗反应）和问卷调查中获得。在LLLT组中，每个目标注射部位用198毫瓦连续波照射两次，每次30秒，焦斑为0.088厘米，施加能量为5.94焦耳，能量密度为67.50焦耳/平方厘米。在数据采集期间从4个时间点记录测量值。
在与上颌或下颌第三磨牙拔除注射部位相关的疼痛体验评分方面，LLLT组和安慰剂组之间没有显著差异。在上颌和下颌区域，LLLT组注射前和注射期间的平均心率均低于安慰剂组。对于任何其余参数，均未观察到统计学上的显著差异。
目前的数据表明，注射前的LLLT不能有效减轻第三磨牙手术前局部麻醉注射时的疼痛。
