Goran-Kouacou Amah Patricia Victorine, Dou Gonat Serge, Zika Kalou Dibert, Adou Adjoumanvoulé Honoré, Yéboah Oppong Richard, Aka Rita Ahou, Hien Sansan, Siransy Kouabla Liliane, N'Guessan Koffi, Djibangar Tariam Agnès, Dassé Séry Romuald, Adoubryn Koffi Daho
Département d'Immunologie, UFR Sciences Médicales d'Abidjan, Université Félix Houphouët-Boigny.
Département de Parasitologie, UFR Sciences Médicales d'Abidjan, Université Félix Houphouët-Boigny.
Pan Afr Med J. 2017 Apr 24;26:221. doi: 10.11604/pamj.2017.26.221.11314. eCollection 2017.
Malaria serology test seems to have attracted very little interest in endemic countries such as Ivory Coast. However, this examination has been regularly performed in the parasitology laboratory at the Training and Research Unit of Medical Sciences in Abidjan. Our study aimed to highlight the contribution of malaria serology test in our endemic country context.
We conducted a retrospective study of malaria serology test using Falciparum-Spot IF (bioMerieux) kit for the detection of IgG antiplasmodial antibodies. It included all malaria serology tests performed from January 2007 to February 2011 and whose results were available in the registry.
In total, 136 patients were selected. The average age of patients was 36,3 years, ranging from 1 to 81 years, and sex ratio was 0,97. Indications for malaria serology test were varied and dominated by splenomegaly (49.3%), cytopenias (14.7%), indeterminate fever (13.2%). Almost all of the patients (98.5%) had antiplasmodial antibodies with high medium titer of 1057,35IU/ml. There was no link between age and Ab titer, which was higher in cytopenias, prolonged fevers and the splenomegaly.
Malaria serology test seems to have attracted very little interest in routine clinical practice provided in our endemic area because, whatever the reason of the prescription, titers were high.
在科特迪瓦等疟疾流行国家，疟疾血清学检测似乎很少受到关注。然而，阿比让医学科学培训与研究单位的寄生虫学实验室一直在定期开展这项检测。我们的研究旨在凸显疟疾血清学检测在我们这个疟疾流行国家的作用。
我们使用恶性疟原虫斑点免疫荧光法（bioMerieux）试剂盒进行疟疾血清学检测，以检测抗疟原虫IgG抗体，开展了一项回顾性研究。研究纳入了2007年1月至2011年2月期间进行的所有疟疾血清学检测，且其结果已登记在册。
总共选取了136例患者。患者的平均年龄为36.3岁，年龄范围为1至81岁，性别比为0.97。疟疾血清学检测的指征各不相同，以脾肿大（49.3%）、血细胞减少（14.7%）、不明原因发热（13.2%）为主。几乎所有患者（98.5%）都有抗疟原虫抗体，中等滴度较高，为1057.35IU/ml。年龄与抗体滴度之间没有关联，血细胞减少、长期发热和脾肿大患者的抗体滴度更高。
在我们这个疟疾流行地区的常规临床实践中，疟疾血清学检测似乎很少受到关注，因为无论检测的原因是什么，抗体滴度都很高。
