a Department of Brain and Behavioral Sciences , University of Pavia , Pavia , Italy.
b The Grieg Academy Music Therapy Research Centre , Uni Research Health, Uni Research , Bergen , Norway.
Aging Ment Health. 2018 Sep;22(9):1097-1106. doi: 10.1080/13607863.2017.1348474. Epub 2017 Jul 10.
The aim of the present study was to meta-analyze the effect of music therapy (MT) on cognitive functions in patients with dementia.
A systematic literature search was performed in Medline, PsycINFO, Embase, CINAHL and RILM up to 8 September 2016. We included all randomized controlled trials that compared MT with standard care, or other non-musical types of intervention, evaluating cognitive outcomes in patients with dementia. Outcomes included global cognition, complex attention, executive function, learning and memory, language, and perceptual-motor skills.
From 1089 potentially relevant records, 110 studies were assessed for eligibility, and 7 met the inclusion criteria, of which 6 contained appropriate data for meta-analysis (330 participants, mean age range 78.8-86.3). Overall, random-effects meta-analyses suggested no significant effects of MT on all outcomes. Subgroup analysis found evidence of a beneficial effect of active MT on global cognition (SMD = 0.29, 95% CI 0.02 to 0.57, p = 0.04).
Despite the limited evidence of the present review, it is important to continue supporting MT as a complementary treatment for older adults with dementia. RCTs with larger sample sizes are needed to better elucidate the impact of MT on cognitive functions.
本研究旨在荟萃分析音乐治疗（MT）对痴呆患者认知功能的影响。
系统检索了 Medline、PsycINFO、Embase、CINAHL 和 RILM 数据库，检索时间截至 2016 年 9 月 8 日。我们纳入了所有比较 MT 与标准护理或其他非音乐干预措施、评估痴呆患者认知结局的随机对照试验。结局包括总体认知、复杂注意力、执行功能、学习和记忆、语言以及知觉运动技能。
从 1089 篇潜在相关记录中，评估了 110 项研究的纳入资格，其中 7 项符合纳入标准，其中 6 项包含适合荟萃分析的数据（330 名参与者，平均年龄范围 78.8-86.3）。总体而言，随机效应荟萃分析表明 MT 对所有结局均无显著影响。亚组分析发现，主动 MT 对总体认知有有益影响（SMD=0.29，95%CI 0.02 至 0.57，p=0.04）。
尽管本综述的证据有限，但仍有必要继续支持 MT 作为痴呆老年患者的一种补充治疗方法。需要更大样本量的 RCT 来更好地阐明 MT 对认知功能的影响。
