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激光在皮肤癌治疗中的应用:综述

The use of lasers in the treatment of skin cancer: A review.

作者信息

Mirza Fatima N, Khatri Khalil A

机构信息

a Department of Dermatology, Yale School of Medicine , Yale University , New Haven , CT , USA.

b Department of Public Health and Primary Care , University of Cambridge , Cambridge , UK.

出版信息

J Cosmet Laser Ther. 2017 Dec;19(8):451-458. doi: 10.1080/14764172.2017.1349321. Epub 2017 Jul 10.

Abstract

BACKGROUND

In considering skin cancer, a number of factors-including effectiveness, simplicity of treatment, cost, and esthetic outcomes-are important to ensure patient's satisfaction. There are several existing interventions, such as electrodessication and curettage, excision, Mohs surgery, radiation therapy, cryotherapy, and topical/oral treatments. Laser therapy has emerged as a new promising alternative that should be explored.

OBJECTIVE

To review the literature on the dermatological use of laser therapy in the treatment of skin cancer.

RESULTS

A review of articles available on the MEDLINE and Web of Science databases until May 2017 yielded 24 and 6 studies, respectively, on laser therapy in the treatment of skin cancers, particularly melanoma, basal cell carcinoma, and squamous cell carcinoma. The four laser subtypes included solid-state, diode, dye, and gas lasers.

CONCLUSION

Review of the literature demonstrates the progress of dermatological understanding of the clinical implications of laser therapy in the treatment of premalignant and malignant neoplasms of the skin, and suggests that this treatment modality might be a viable option for some patients.

摘要

背景

在考虑皮肤癌时,包括有效性、治疗的简易性、成本和美学效果在内的诸多因素对于确保患者满意度至关重要。目前有多种现有干预措施,如电干燥刮除术、切除术、莫氏手术、放射治疗、冷冻疗法以及局部/口服治疗。激光疗法已成为一种值得探索的新的有前景的替代方法。

目的

回顾关于激光疗法在皮肤科用于治疗皮肤癌的文献。

结果

对截至2017年5月MEDLINE和科学网数据库中可得文章的回顾分别产生了24项和6项关于激光疗法治疗皮肤癌,特别是黑色素瘤、基底细胞癌和鳞状细胞癌的研究。四种激光亚型包括固态、二极管、染料和气体激光器。

结论

文献回顾展示了皮肤科对激光疗法在治疗皮肤癌前病变和恶性肿瘤方面临床意义的认识进展,并表明这种治疗方式可能对某些患者是一种可行的选择。

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