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优化外耳道炎中耳棉条的使用

Optimising the use of otowicks in otitis externa.

作者信息

Bola S, Rashid M, Hickey S

机构信息

Department of Otolaryngology,Torbay and South Devon NHS Foundation Trust,Torquay,UK.

出版信息

J Laryngol Otol. 2017 Sep;131(9):809-812. doi: 10.1017/S002221511700144X. Epub 2017 Jul 11.

Abstract

OBJECTIVE

Otowicks are used to treat otitis externa with significant ear canal oedema. This study investigates how well drops penetrate through to reach the deep canal and whether it is safe to leave otowicks in the canal for more than 2 days.

METHODS

Sterile otowicks were inserted into mock ear canals and vertically over pseudomonas-seeded agar plates whilst gentamicin or ciprofloxacin drops were administered. The time taken for drops to penetrate through the otowick was recorded. Separately, pseudomonas-seeded otowicks were treated with saline or antibacterial drops. The penetrating drops were observed for bacterial growth on sterile agar.

RESULTS

It took six drops before penetration occurred for both antibiotics. When sterile saline drops were applied to bacterially contaminated otowicks, the penetrating drops displayed bacterial growth on agar, indicating that pseudomonas penetrated through the otowick. However, when antibiotic drops were applied, penetrating drops showed no bacterial growth on the corresponding agar plate.

CONCLUSION

Bacteria can penetrate otowicks but this is prevented by continuous application of antibacterial ear drops. Ear wicks need priming with six drops before starting a regimen, so that the initial dose is fully absorbed.

摘要

目的

耳芯用于治疗伴有严重耳道水肿的外耳道炎。本研究调查滴耳剂渗透至耳道深部的效果如何,以及将耳芯留在耳道内超过2天是否安全。

方法

将无菌耳芯插入模拟耳道,并垂直置于接种了铜绿假单胞菌的琼脂平板上方,同时滴入庆大霉素或环丙沙星滴耳剂。记录滴耳剂穿透耳芯所需的时间。另外,对接种了铜绿假单胞菌的耳芯用生理盐水或抗菌滴耳剂进行处理。观察穿透的滴耳剂在无菌琼脂上的细菌生长情况。

结果

两种抗生素均需滴入6滴才会发生穿透。当将无菌生理盐水滴入被细菌污染的耳芯时,穿透的滴耳剂在琼脂上显示出细菌生长,表明铜绿假单胞菌穿透了耳芯。然而,当滴入抗生素滴耳剂时,穿透的滴耳剂在相应的琼脂平板上未显示细菌生长。

结论

细菌可穿透耳芯,但持续使用抗菌滴耳剂可防止这种情况发生。在开始治疗方案前,耳芯需要用6滴药液进行预充,以便初始剂量能被充分吸收。

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