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系统性红斑狼疮性脊髓炎

Myelitis in systemic lupus erythematosus.

作者信息

Li Xiang-Yang, Xiao Hai-Bing, Pai Pearl

机构信息

Department of Nephrology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.

Department of Neurology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.

出版信息

J Clin Neurosci. 2017 Oct;44:18-22. doi: 10.1016/j.jocn.2017.06.003. Epub 2017 Jul 8.

Abstract

SLE-associated acute transverse myelitis (ATM) is a rare, but potentially severe complication of Systemic lupus erythematosus (SLE), and may lead to significant motor, sensory and autonomic dysfunctions in the central nervous system resulting in marked neurological deficits. It is important to recognize its clinical feature to allow timely diagnosis and management of this condition. In this review, we aimed to provide the reader with the understanding of its clinical presentation and classification, the underlying pathological, MRI (magnetic resonance imaging) appearance, and current status of management, with an emphasis on recent discoveries and advancements.

摘要

系统性红斑狼疮(SLE)相关的急性横贯性脊髓炎(ATM)是一种罕见但可能严重的系统性红斑狼疮并发症,可导致中枢神经系统出现明显的运动、感觉和自主神经功能障碍,从而造成显著的神经功能缺损。认识其临床特征对于及时诊断和处理这种情况很重要。在本综述中,我们旨在让读者了解其临床表现和分类、潜在病理、磁共振成像(MRI)表现以及当前的处理现状,重点介绍近期的发现和进展。

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