Chinnaiyan Sowmya, Narayana Sarala, Nanjappa Venkatarathnamma Puttappa
Department of Pharmacology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India.
Department of Medicine, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India.
J Neurosci Rural Pract. 2017 Jul-Sep;8(3):417-420. doi: 10.4103/jnrp.jnrp_392_16.
Epilepsy is a neurological disorder affecting 70 million worldwide. The high incidence of relapse can be attributed to nonadherence, thus increasing the incidence of refractory epilepsy to 10%-20%.
This study was planned to determine rate of adherence and factors affecting adherence using Antiepileptic Adherence Questionnaire and Baseline Adherence Questionnaire.
A cross-sectional, questionnaire-based study was carried out at a rural hospital from May to September 2015. Patients of either gender aged 18-60 years, diagnosed with epilepsy were interviewed after they consented. Patient details, responses to questionnaires were collected and analyzed using descriptive statistics.
Among the participants, 67.8% were males and 32.2% were females with the mean age of 38.3 ± 13.9 years. The response rate was 75% (90/120). The majority were literate (64.4%) and employed (58.9%). The duration of disease was <5 years in most individuals; 50% were highly, 21.1% moderately, and 28.9% nonadherent to treatment. Among the highly adherent, 66.7% never skipped medications because they had knowledge of the disease and treatment. More than 97% were satisfied with the social support, and 89% expressed that their family and friends reminded them to take medications. Patients who were nonadherent to treatment attributed it to the lack of knowledge of the disease (57%) and treatment (96%). Reasons for nonadherence were patients assumed drug was harmful, felt cured of the disease, and wanted to avoid side effects.
Nearly, 70% expressed the lack of satisfactory support from the social circle. We observed that nearly seventy percent epileptic patients were moderate-highly adherent. Nonadherence was attributed to patient feeling cured of disease and assuming medications to be harmful. Counseling of patients will help in adherence to treatment.
癫痫是一种影响全球7000万人的神经系统疾病。复发率高可归因于治疗依从性差，从而使难治性癫痫的发病率增加到10%-20%。
本研究旨在使用抗癫痫药物依从性问卷和基线依从性问卷来确定依从率以及影响依从性的因素。
2015年5月至9月在一家乡村医院开展了一项基于问卷的横断面研究。年龄在18-60岁、被诊断为癫痫的患者在同意后接受访谈。收集患者详细信息、问卷回复，并使用描述性统计方法进行分析。
参与者中，男性占67.8%，女性占32.2%，平均年龄为38.3±13.9岁。回复率为75%（90/120）。大多数人识字（64.4%）且有工作（58.9%）。大多数人的病程<5年；50%的人治疗依从性高，21.1%的人中等，28.9%的人不依从治疗。在依从性高的人群中，66.7%的人从未漏服药物，因为他们了解疾病和治疗方法。超过97%的人对社会支持感到满意，89%的人表示家人和朋友会提醒他们服药。不依从治疗的患者将其归因于对疾病（57%）和治疗（96%）缺乏了解。不依从的原因包括患者认为药物有害、觉得疾病已治愈以及想避免副作用。
近70%的人表示社会圈子缺乏令人满意的支持。我们观察到近70%的癫痫患者依从性为中等偏高。不依从归因于患者觉得疾病已治愈以及认为药物有害。对患者进行咨询将有助于提高治疗依从性。
