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老年2型糖尿病的治疗

Treatment of type 2 diabetes mellitus in the elderly.

作者信息

Yakaryılmaz Funda Datli, Öztürk Zeynel Abidin

机构信息

Funda Datli Yakaryılmaz, Zeynel Abidin Öztürk, Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Gaziantep University, 27100 Sahinbey, Gaziantep, Turkey.

出版信息

World J Diabetes. 2017 Jun 15;8(6):278-285. doi: 10.4239/wjd.v8.i6.278.

DOI:10.4239/wjd.v8.i6.278
PMID:28694928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5483426/
Abstract

The prevalence of type 2 diabetes is expected to increase gradually with the prolongation of population aging and life expectancy. In addition to macrovascular and microvascular complications of elderly patients of diabetes mellitus, geriatric syndromes such as cognitive impairment, depression, urinary incontinence, falling and polypharmacy are also accompanied by aging. Individual functional status in the elderly shows heterogeneity so that in these patients, there are many unanswered questions about the management of diabetes treatment. The goals of diabetes treatment in elderly patients include hyperglycemia and risk factors, as in younger patients. comorbid diseases and functional limitations of individuals should be taken into consideration when setting treatment targets. Thus, treatment should be individualized. In the treatment of diabetes in vulnerable elderly patients, hypoglycemia, hypotension, and drug interactions due to multiple drug use should be avoided. Since it also affects the ability to self-care in these patients, management of other concurrent medical conditions is also important.

摘要

随着人口老龄化和预期寿命的延长,2型糖尿病的患病率预计将逐渐上升。除了糖尿病老年患者的大血管和微血管并发症外,认知障碍、抑郁、尿失禁、跌倒和多重用药等老年综合征也伴随着衰老出现。老年人的个体功能状态存在异质性,因此在这些患者中,关于糖尿病治疗管理仍有许多未解决的问题。老年患者的糖尿病治疗目标与年轻患者一样,包括高血糖和危险因素。在设定治疗目标时应考虑个体的合并疾病和功能限制。因此,治疗应个体化。在治疗脆弱的老年糖尿病患者时,应避免低血糖、低血压以及因多种药物联用导致的药物相互作用。由于这也会影响这些患者的自我护理能力,因此管理其他并存的医疗状况也很重要。

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本文引用的文献

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Diabetes Obes Metab. 2017 Jun;19(6):831-841. doi: 10.1111/dom.12889. Epub 2017 Mar 16.
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American Diabetes Association Standards of Medical Care in Diabetes 2017.《2017年美国糖尿病协会糖尿病医疗护理标准》
J Diabetes. 2017 Apr;9(4):320-324. doi: 10.1111/1753-0407.12524.
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