Volpe Daniele, Pelosin Elisa, Bakdounes Leila, Masiero Stefano, Bertagnoni Giannettore, Sorbera Chiara, Giantin Maria Giulia
Department of Physical Medicine and Rehabilitation, Neurorehabilitation Unit "Villa Margherita,", Via Costacolonna n.6 Arcugnano, Vicenza, Italy.
Department of Neuroscience, University of Genoa, Genoa, Italy.
J Clin Mov Disord. 2017 Jul 6;4:11. doi: 10.1186/s40734-017-0058-y. eCollection 2017.
Proprioceptive deficits have been largely documented in PD patients, thus external sensory signals (peripheral sensory feedback) are often used to compensate the abnormalities of proprioceptive integration. This pilot study aims to evaluate the feasibility and the effectiveness of a rehabilitation-training program, combined with the use of a sensory-motor orthotic in improving balance in a small sample of PD patients.
Twenty PD patients were randomly allocated into two groups: (i) , where participants were asked to wear a sensory-motor orthotic during the balance training program and (ii) , where subjects performed an identical training program without wearing any kind of orthotics. In all, the training program lasted 10 sessions (5 days a week for 2 weeks) and the clinical and instrumental assessments were performed at baseline, immediately after the end of the training and 4 weeks after the rehabilitative program was stopped.
All clinical outcome measures tested improved significantly at post and follow-up evaluations in both groups. Interestingly, at the end of the training, only the experimental group obtained a significant improvement in the functional reaching test (sway area - eyes closed) measured by means of stabilometric platform and this result was maintained in the follow-up evaluation.
Our preliminary results suggested that the use of a sensory-motor orthotic, in combination with a tailored balance training, is feasible and it seems to positively impact on balance performance in Parkinson's disease.
EudraCT N. 003020-36 - 2013.
本体感觉缺陷在帕金森病（PD）患者中已有大量记录，因此外部感觉信号（外周感觉反馈）常被用于补偿本体感觉整合异常。这项初步研究旨在评估一项康复训练计划结合使用感觉运动矫形器对一小部分PD患者平衡能力改善的可行性和有效性。
20名PD患者被随机分为两组：（i）实验组，参与者在平衡训练计划期间被要求佩戴感觉运动矫形器；（ii）对照组，受试者进行相同的训练计划但不佩戴任何矫形器。总体而言，训练计划持续10次（每周5天，共2周），临床和仪器评估在基线、训练结束后立即以及康复计划停止4周后进行。
两组在训练后和随访评估中，所有测试的临床结局指标均有显著改善。有趣的是，在训练结束时，只有实验组在通过稳定测力平台测量的功能性伸展测试（闭眼摇摆面积）中获得了显著改善，且这一结果在随访评估中得以维持。
我们的初步结果表明，使用感觉运动矫形器结合量身定制的平衡训练是可行的，并且似乎对帕金森病的平衡表现有积极影响。
EudraCT编号003020 - 36 - 2013 。
