Siaw-Debrah Felix, Nyanzu Mark, Ni Haoqi, Lin Xiao, Xu Zhu, Ruan Linhui, Zhuge Qichuan, Huang Lijie
Department of Neurosurgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Zhejiang Provincial Key Laboratory of Aging and Neurological Disorder Research, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325000, China.
Biomed Res Int. 2017;2017:5135429. doi: 10.1155/2017/5135429. Epub 2017 Jun 18.
Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment options like stem cell therapy, rehabilitation, and nanomedicine and mention some translational clinical applications that have been done with these treatment options.
脑出血（ICH）是指脑内出血，是一种非常有害的疾病，死亡率和致残率很高。手术或保守治疗仍然是治疗选择。各种研究已将脑出血的疾病过程分为原发性和继发性损伤，对这些过程的了解产生了许多临床前和临床治疗选择。本综述的目的是强调一些新的实验性药物以及其他治疗选择，如干细胞治疗、康复治疗和纳米医学，并提及已通过这些治疗选择进行的一些转化临床应用。
