Letsyo Emmanuel, Jerz Gerold, Winterhalter Peter, Dübecke Arne, von der Ohe Werner, von der Ohe Katharina, Beuerle Till
a Institut für Lebensmittelchemie , Technische Universität Braunschweig , Braunschweig , Germany.
b Research and Development Department , Quality Services International GmbH , Bremen , Germany.
Food Addit Contam Part B Surveill. 2017 Dec;10(4):300-310. doi: 10.1080/19393210.2017.1354336. Epub 2017 Jul 16.
There is a vast amount of information about the nutritional and medicinal properties of honey as a result of its numerous benefits. However, honeys have been found to be contaminated with hepatotoxic and carcinogenic pyrrolizidine alkaloids (PAs) on account of bees foraging on PA-containing plants. This study deals with the analysis of PAs in tropical honeys emanating from different agro-ecological zones of Ghana in order to assess its potential health risk. PAs of 48 honey samples were analysed using high-performance liquid chromatography-electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). The results show that a total of 85% of the honeys from various agro-ecological zones were PA positive including all honeys from supermarkets. The highest concentration of PAs was 2639 μg kg, while the average PA concentration of the samples was 283 μg kg. The study also found Chromolaena odorata pollens in majority of the honeys, thus indicating the plant as major source of PA contamination of honeys in the tropical regions.
由于蜂蜜具有诸多益处，关于其营养和药用特性的信息海量。然而，由于蜜蜂采集含吡咯里西啶生物碱（PAs）的植物，已发现蜂蜜被肝毒性和致癌性的吡咯里西啶生物碱污染。本研究旨在分析来自加纳不同农业生态区的热带蜂蜜中的PAs，以评估其潜在健康风险。使用高效液相色谱-电喷雾电离串联质谱法（HPLC-ESI-MS/MS）分析了48个蜂蜜样品中的PAs。结果表明，来自不同农业生态区的蜂蜜中共有85%的样品PAs呈阳性，包括超市里的所有蜂蜜。PAs的最高浓度为2639μg/kg，而样品的平均PA浓度为283μg/kg。该研究还在大多数蜂蜜中发现了香丝草花粉，因此表明该植物是热带地区蜂蜜中PA污染的主要来源。
