Harvey Valerie M, Enos Clinton W, Chen Jarvis T, Galadima Hadiza, Eschbach Karl
Department of Dermatology, Eastern Virginia Medical School, Norfolk, VA, USA.
Hampton University Skin of Color Research Institute, Hampton, VA, USA.
J Cancer Epidemiol. 2017;2017:8418904. doi: 10.1155/2017/8418904. Epub 2017 Jun 18.
Hispanics diagnosed with cutaneous melanoma are more likely to present at advanced stages but the reasons for this are unknown. We identify at high risk for late stage melanoma diagnosis (LSMD) and examine the contextual predictors of LSMD in California, Texas, and Florida.
We conducted a cross-sectional study using geocoded state cancer registry data. Using hierarchical multilevel logistic regression models we estimated ORs and 95% confidence intervals for the impact of socioeconomic, Hispanic ethnic concentration, index of dissimilarity, and health resource availability measures on LSMD.
We identified 12,493 cases. In California, late stage cases were significantly more likely to reside within census tracts composed mostly of Hispanics and immigrants. In Texas, LSMD was associated with residence in areas of socioeconomic deprivation and a higher proportion of immigrants. In Florida, living in areas of low education attainment, high levels of poverty, and a high percentage of Hispanic residents was significantly associated with LSMD. Residential segregation did not independently affect LSMD.
The influence of contextual predictors on LSMD varied in magnitude and strength by state, highlighting both the cosegregation of social adversity and poverty and the complexity of their interactions.
被诊断为皮肤黑色素瘤的西班牙裔患者更有可能在晚期发病,但其原因尚不清楚。我们确定了晚期黑色素瘤诊断(LSMD)的高风险因素,并研究了加利福尼亚州、得克萨斯州和佛罗里达州LSMD的背景预测因素。
我们使用地理编码的州癌症登记数据进行了一项横断面研究。我们使用分层多级逻辑回归模型,估计社会经济、西班牙裔种族集中度、差异指数和卫生资源可及性指标对LSMD的影响的比值比(OR)和95%置信区间。
我们确定了12493例病例。在加利福尼亚州,晚期病例更有可能居住在主要由西班牙裔和移民组成的普查区。在得克萨斯州,LSMD与居住在社会经济贫困地区和较高比例的移民有关。在佛罗里达州,生活在低教育程度、高贫困水平和高比例西班牙裔居民的地区与LSMD显著相关。居住隔离并未独立影响LSMD。
背景预测因素对LSMD的影响在不同州的程度和强度各不相同,这突出了社会逆境和贫困的共同存在及其相互作用的复杂性。