皮肤微生态失调走向“失控”。

Skin Dysbiosis Goes "Off-Leish".

机构信息

Department of Dermatology, University of California, San Francisco, CA 94143, USA.

出版信息

Cell Host Microbe. 2017 Jul 12;22(1):1-3. doi: 10.1016/j.chom.2017.06.017.

DOI:10.1016/j.chom.2017.06.017

Abstract

There is increasing interest in the contribution of microbes to skin disease. In this issue of Cell Host & Microbe, Gimblet et al. (2017) demonstrate that cutaneous leishmaniasis alters the human skin microbiota. In mice, this dysbiosis is transferable to naive animals, where it augments skin inflammation and disease severity.

摘要

人们对微生物在皮肤病中的作用越来越感兴趣。在本期《Cell Host & Microbe》杂志上，Gimblet 等人（2017）表明，皮肤利什曼病改变了人类皮肤微生物组。在小鼠中，这种微生态失调可以转移到未感染的动物身上，从而增强皮肤炎症和疾病的严重程度。