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一例老年肾功能不全患者头孢曲松相关的胆汁假性结石病例。

A case of ceftriaxone-associated biliary pseudolithiasis in an elderly patient with renal dysfunction.

作者信息

Abe Shuichi

机构信息

Rehabilitation Oomiko Hospital, Internal Medicine. Oomiko19, Oohara-cho, Tokushima-city, Tokushima, 770-8012, Japan.

出版信息

IDCases. 2017 Jun 27;9:62-64. doi: 10.1016/j.idcr.2017.06.007. eCollection 2017.

DOI:10.1016/j.idcr.2017.06.007
PMID:28706853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5499111/
Abstract

Prior literature suggests that ceftriaxone causes formation of gallbladder stones at a relatively high frequency, and when abdominal symptoms occur, prompt investigation of the gallbladder is required with institution of appropriate treatment. Aging, malnutrition, renal impairment, and sepsis are risk factors for pseudolithiasis, and prevention of these is important to suppress gallstone development.

摘要

既往文献表明，头孢曲松相对频繁地导致胆囊结石形成，当出现腹部症状时，需要对胆囊进行及时检查并采取适当治疗。年龄增长、营养不良、肾功能损害和脓毒症是假结石形成的危险因素，预防这些因素对于抑制胆结石发展很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/5499111/6fb5f67fb8c8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/5499111/6fb5f67fb8c8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c6/5499111/6fb5f67fb8c8/gr1.jpg

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本文引用的文献

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Fasting and bed rest, even for a relatively short period, are risk factors for ceftriaxone-associated pseudolitiasis.禁食和卧床休息，即使是相对较短的时间，都是与头孢曲松相关的假性结石形成的危险因素。
Pediatr Int. 2015 Oct;57(5):942-6. doi: 10.1111/ped.12625. Epub 2015 Jul 21.
2
Pseudolithiasis due to ceftriaxone treatment for meningitis in children: report of 8 cases.儿童脑膜炎头孢曲松治疗所致假性结石症：8例报告
Tohoku J Exp Med. 2007 Mar;211(3):285-90. doi: 10.1620/tjem.211.285.
3
Ceftriaxone-associated biliary pseudolithiasis in children.
头孢曲松相关胆内假性结石伴老年 1 型糖尿病：两例报告。
Intern Med. 2023 Nov 15;62(22):3367-3371. doi: 10.2169/internalmedicine.1405-22. Epub 2023 Apr 7.
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Rapid Onset of Ceftriaxone-Induced Cholelithiasis in an Adult Patient.一名成年患者中头孢曲松诱导的胆结石症的快速发作
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