Sydney School of Public Health, University of Sydney, Camperdown, NSW, Australia.
Department of Nephrology, Princess Alexandra Hospital, Brisbane, Australia.
Pediatr Nephrol. 2018 Jun;33(6):973-983. doi: 10.1007/s00467-017-3728-y. Epub 2017 Jul 13.
Advances in the care of children mean that adolescents with chronic kidney disease (CKD) are surviving to adulthood and requiring transition to adult care. The transition phase is well-recognised to be associated with considerable excess morbidity and graft loss, but these outcomes may be avoidable through a structured transition programme. This review will discuss the (1) challenges encountered by patients with CKD, caregivers and clinicians during transition; (2) predictors and outcomes of transition; (3) current guidelines on transition from paediatric to adult renal services; (4) interventions and research directions that may help to improve the care and outcomes for young people with CKD in transition. In spite of the substantial improvement in health gains required for this disadvantaged population, there is to date only limited evidence on the effects of current transition programmes.
儿童保健的进步意味着患有慢性肾脏疾病 (CKD) 的青少年能够存活到成年期,并需要过渡到成人护理。人们已经认识到,过渡阶段与相当大的发病率和移植物丢失有关,但通过结构化的过渡计划,这些结果是可以避免的。这篇综述将讨论:(1)CKD 患者、照顾者和临床医生在过渡期间面临的挑战;(2)过渡的预测因素和结果;(3)从儿科到成人肾脏服务的现行过渡指南;(4)可能有助于改善过渡期间青少年 CKD 患者护理和结果的干预措施和研究方向。尽管在为这一弱势群体带来健康收益方面取得了重大进展,但迄今为止,关于现行过渡计划效果的证据有限。