de la Rubia Ortí José Enrique, García-Pardo María Pilar, Iranzo Carmen Cabañés, Madrigal José Joaquin Cerón, Castillo Sandra Sancho, Rochina Mariano Julián, Gascó Vicente Javier Prado
1 Department of Dentistry, European University of Valencia , Valencia, Spain .
2 Faculty of Psychology, European University of Valencia , Valencia, Spain .
J Altern Complement Med. 2018 Jan;24(1):33-36. doi: 10.1089/acm.2016.0346. Epub 2017 Jul 17.
To evaluate the effectiveness of the implementation of a short protocol of music therapy as a tool to reduce stress and improve the emotional state in patients with mild Alzheimer's disease.
A sample of 25 patients with mild Alzheimer's received therapy based on the application of a music therapy session lasting 60 min. Before and after the therapy, patient saliva was collected to quantify the level of salivary cortisol using the Enzyme-Linked ImmunoSorbent Assay (ELISA) immunoassay technique and a questionnaire was completed to measure anxiety and depression (Hospital Anxiety and Depression Scale).
The results show that the application of this therapy lowers the level of stress and decreases significantly depression and anxiety, establishing a linear correlation between the variation of these variables and the variation of cortisol.
A short protocol of music therapy can be an alternative medicine to improve emotional variables in Alzheimer patients.
评估实施简短音乐治疗方案作为减轻轻度阿尔茨海默病患者压力和改善其情绪状态工具的有效性。
25名轻度阿尔茨海默病患者样本接受了基于时长60分钟音乐治疗课程的治疗。治疗前后，收集患者唾液，采用酶联免疫吸附测定（ELISA）免疫测定技术定量唾液皮质醇水平，并完成一份问卷以测量焦虑和抑郁（医院焦虑抑郁量表）。
结果表明，这种治疗方法可降低压力水平，并显著减轻抑郁和焦虑，这些变量的变化与皮质醇变化之间建立了线性相关性。
简短的音乐治疗方案可作为改善阿尔茨海默病患者情绪变量的替代医学手段。
