Papazian Tatiana, Abi Tayeh Georges, Sibai Darine, Hout Hala, Melki Imad, Rabbaa Khabbaz Lydia
Laboratoire de Pharmacologie, Pharmacie Clinique et Contrôle de Qualité des Médicaments, Faculty of Pharmacy, Saint-Joseph University of Beirut, Beirut, Lebanon.
Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Beirut, Lebanon.
PLoS One. 2017 Jul 17;12(7):e0181255. doi: 10.1371/journal.pone.0181255. eCollection 2017.
Studies on the relative impact of body mass index in women in childbearing age and gestational weight gain on neonatal outcomes are scarce in the Middle East.
The primary objective of this research was to assess the impact of maternal body mass index (BMI) and gestational weight gain (GWG) on neonatal outcomes. The effect of maternal age and folic acid supplementation before and during pregnancy was also examined.
This is a retrospective cross sectional observational study of 1000 full term deliveries of women enrolled thru the National Collaborative Perinatal Neonatal Network, in Lebanon. Maternal characteristics such as age, BMI and GWG and neonatal outcomes such as weight, height, head circumference and Apgar score were the primary studied variables in this study. Total maternal weight gain were compared to the guidelines depicted by the Institute of Medicine (IOM).
The negative outcomes of newborns such as lean body weight and macrosomia were significantly present in women who gained respectively below or above the IOM's cut-off points. Pregestational body mass index influenced significantly the infants' birth weight, in both the underweight and obese categories. Birth height, head circumference and Apgar score were not influenced by pregestational body mass index or gestational weight gain. No significant associations were found between maternal age and pregestational body mass index and gestational weight gain.
Studies evaluating the impact of weight before and during pregnancy on neonatal outcomes and anthropometrics measurements are lacking in the Middle East. Our results highlight the importance of nutritional counseling in order to shed the extra weights before conceiving and monitor weight gain to avoid the negative impact on feto-maternal health.
在中东地区，关于育龄期女性体重指数和孕期体重增加对新生儿结局的相对影响的研究很少。
本研究的主要目的是评估孕妇体重指数（BMI）和孕期体重增加（GWG）对新生儿结局的影响。还研究了孕妇年龄以及孕期前后叶酸补充的影响。
这是一项对黎巴嫩通过国家围产期新生儿协作网络登记的1000例足月分娩妇女进行的回顾性横断面观察研究。孕妇的特征如年龄、BMI和GWG，以及新生儿结局如体重、身高、头围和阿氏评分是本研究的主要研究变量。将孕妇的总体重增加与医学研究所（IOM）描述的指南进行比较。
体重增加分别低于或高于IOM切点的女性中，新生儿的负面结局如低体重和巨大儿显著存在。孕前体重指数对体重过轻和肥胖类别的婴儿出生体重有显著影响。出生时的身高、头围和阿氏评分不受孕前体重指数或孕期体重增加的影响。未发现孕妇年龄与孕前体重指数和孕期体重增加之间存在显著关联。
中东地区缺乏评估孕前和孕期体重对新生儿结局和人体测量学指标影响的研究。我们的结果强调了营养咨询的重要性，以便在怀孕前减轻多余体重并监测体重增加，以避免对母婴健康产生负面影响。
