Goker Yasin Sakir, Yuksel Kemal, Turan Miray Faiz, Sonmez Kenan, Tekin Kemal, Yilmazbas Pelin
Ophthalmic Surg Lasers Imaging Retina. 2018 Jan 1;49(1):41-47. doi: 10.3928/23258160-20171215-06.
To determine possible changes in thickness profiles of retinal layers in patients with rhegmatogenous retinal detachment (RRD) treated with perfluoropropane (C3F8) or silicon oil (SiO).
Seventy-two eyes of 36 patients were enrolled in this retrospective comparative study. Patients were divided into two groups according to intraocular tamponade: C3F8 or SiO. All study eyes were compared with fellow eyes via spectral-domain optical coherence tomography segment analysis at 6 months postoperatively. Macular layer thicknesses including retinal nerve fiber layer, ganglion cell layer, inner plexiform layer, inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), and retinal pigment epithelium were analyzed.
There was a statistically significant difference between eyes in terms of INL thickness (P = .044) in C3F8 group. Otherwise there was a statistically significant difference between eyes in terms of INL, OPL, and ONL thicknesses (P = .006, P = .048, and P = .004, respectively) in the SiO group.
The findings of the present study show that the tamponade used in RRD surgery can affect the retinal layers differently. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:41-47.].
确定接受全氟丙烷（C3F8）或硅油（SiO）治疗的孔源性视网膜脱离（RRD）患者视网膜各层厚度分布的可能变化。
本回顾性比较研究纳入了36例患者的72只眼。根据眼内填充剂将患者分为两组：C3F8组或SiO组。所有研究眼在术后6个月通过光谱域光学相干断层扫描节段分析与对侧眼进行比较。分析了包括视网膜神经纤维层、神经节细胞层、内丛状层、内核层（INL）、外丛状层（OPL）、外核层（ONL）和视网膜色素上皮在内的黄斑层厚度。
C3F8组两眼之间在INL厚度方面存在统计学显著差异（P = .044）。此外，SiO组两眼之间在INL、OPL和ONL厚度方面存在统计学显著差异（分别为P = .006、P = .048和P = .004）。
本研究结果表明，RRD手术中使用的填充剂对视网膜各层的影响可能不同。[《眼科手术、激光与影像学杂志》。2018；49：41 - 47。]
