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丹麦男性人乳头瘤病毒疫苗接种的社会经济预测因素——一项全国性研究

Socioeconomic predictors of human papillomavirus vaccination in Danish men - A nationwide study.

作者信息

Bollerup Signe, Baldur-Felskov Birgitte, Dehlendorff Christian, Kjaer Susanne K

机构信息

Virus, Lifestyle and Genes, Danish Cancer Society Research Centre, DK-2100 Copenhagen, Denmark.

Statistics, Bioinformatics and Registry, Danish Cancer Society Research Centre, DK-2100 Copenhagen, Denmark.

出版信息

Papillomavirus Res. 2017 Jun;3:18-23. doi: 10.1016/j.pvr.2016.11.004. Epub 2016 Nov 24.

Abstract

BACKGROUND

The quadrivalent human papillomavirus vaccine was licensed in Denmark in 2006. Unlike women, men are not offered human papillomavirus vaccination free of charge but can have it at their own expense. We investigated human papillomavirus vaccine uptake by men in Denmark and the socioeconomic factors that may predict human papillomavirus vaccination.

METHODS

Using the Civil Registration System, we identified all boys and men aged 9-26 years in 2006-2013 and their mothers. By linkage to Statistics Denmark and the National Prescription Registry, we obtained information on socioeconomic variables and human papillomavirus vaccination during the study period. Using Cox regression, we examined the associations between socioeconomic variables and human papillomavirus vaccination.

RESULTS

Between 2006 and 2013, 6253 (0.8%) males aged 9-26 years were vaccinated against human papillomavirus. The strongest predictor identified was ethnicity. Males who were immigrants (hazard ratio, 0.12; 95% confidence interval, 0.08-0.180) or sons of immigrant parents (hazard ratio, 0.13; 95% confidence interval, 0.10-0.17) were less likely to be vaccinated than Danish males. Additionally, sons of mothers who were unemployed, unmarried, had a low income, and basic education initiated human papillomavirus vaccination less frequently. Finally, sons of mothers who were physicians or nurses were more likely to be vaccinated than sons of other highly educated mothers.

CONCLUSION

We found low uptake, with social disparities in human papillomavirus vaccination of boys and young men in Denmark.

摘要

背景

四价人乳头瘤病毒疫苗于2006年在丹麦获得许可。与女性不同,男性不能免费接种人乳头瘤病毒疫苗,但可以自费接种。我们调查了丹麦男性人乳头瘤病毒疫苗的接种情况以及可能预测人乳头瘤病毒疫苗接种的社会经济因素。

方法

利用民事登记系统,我们确定了2006 - 2013年所有9至26岁的男孩和男性及其母亲。通过与丹麦统计局和国家处方登记处的关联,我们获得了研究期间社会经济变量和人乳头瘤病毒疫苗接种的信息。使用Cox回归,我们研究了社会经济变量与人乳头瘤病毒疫苗接种之间的关联。

结果

2006年至2013年期间,6253名(0.8%)9至26岁的男性接种了人乳头瘤病毒疫苗。确定的最强预测因素是种族。移民男性(风险比,0.12;95%置信区间,0.08 - 0.180)或移民父母的儿子(风险比,0.13;95%置信区间,0.10 - 0.17)比丹麦男性接种疫苗的可能性更小。此外,母亲失业、未婚、低收入且接受基础教育的儿子接种人乳头瘤病毒疫苗的频率较低。最后,母亲是医生或护士的儿子比其他受过高等教育母亲的儿子更有可能接种疫苗。

结论

我们发现丹麦男孩和年轻男性人乳头瘤病毒疫苗接种率较低,且存在社会差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d5b/5883232/08d609e882a3/gr1.jpg

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