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1
Family Cluster Analysis of Severe Fever with Thrombocytopenia Syndrome Virus Infection in Korea.韩国严重发热伴血小板减少综合征病毒感染的家庭聚集性分析
Am J Trop Med Hyg. 2016 Dec 7;95(6):1351-1357. doi: 10.4269/ajtmh.16-0527. Epub 2016 Oct 17.
2
Mutational and functional analysis of N-linked glycosylation of envelope fusion protein F of Helicoverpa armigera nucleopolyhedrovirus.棉铃虫核型多角体病毒包膜融合蛋白F的N-糖基化的突变与功能分析
J Gen Virol. 2016 Apr;97(4):988-999. doi: 10.1099/jgv.0.000404. Epub 2016 Jan 14.
3
Nosocomial transmission of severe fever with thrombocytopenia syndrome in Korea.韩国严重发热伴血小板减少综合征的医院感染传播。
Clin Infect Dis. 2015 Jun 1;60(11):1681-3. doi: 10.1093/cid/civ128. Epub 2015 Feb 18.
4
A cluster of person-to-person transmission cases caused by SFTS virus in Penglai, China.中国蓬莱由发热伴血小板减少综合征病毒引起的一组人际传播病例。
Clin Microbiol Infect. 2015 Mar;21(3):274-9. doi: 10.1016/j.cmi.2014.10.006. Epub 2014 Oct 29.
5
Person-to-person asymptomatic infection of severe fever with thrombocytopenia syndrome virus through blood contact.发热伴血小板减少综合征病毒通过血液接触引起的人传人无症状感染。
Intern Med. 2014;53(8):903-6. doi: 10.2169/internalmedicine.53.1164. Epub 2014 Apr 15.
6
Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antiviral platform.通过将TBK1/IKKε与线粒体抗病毒平台进行空间隔离，病毒对先天免疫的抑制作用
J Mol Cell Biol. 2014 Aug;6(4):324-37. doi: 10.1093/jmcb/mju015. Epub 2014 Apr 4.
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Human-to-human transmission of severe fever with thrombocytopenia syndrome bunyavirus through contact with infectious blood.严重发热伴血小板减少综合征布尼亚病毒通过接触感染性血液在人与人之间传播。
J Infect Dis. 2013 Mar 1;207(5):736-9. doi: 10.1093/infdis/jis748. Epub 2012 Dec 6.
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A cluster of cases of human-to-human transmission caused by severe fever with thrombocytopenia syndrome bunyavirus.由发热伴血小板减少综合征布尼亚病毒引起的人传人聚集性病例。
Int J Infect Dis. 2013 Mar;17(3):e206-8. doi: 10.1016/j.ijid.2012.11.006. Epub 2012 Dec 6.
9
Clinical progress and risk factors for death in severe fever with thrombocytopenia syndrome patients.严重发热伴血小板减少综合征患者的临床进展和死亡风险因素。
J Infect Dis. 2012 Oct 1;206(7):1095-102. doi: 10.1093/infdis/jis472. Epub 2012 Jul 30.
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一起由人传人引起的发热伴血小板减少综合征的有症状和无症状感染聚集性病例

A Cluster of Symptomatic and Asymptomatic Infections of Severe Fever with Thrombocytopenia Syndrome Caused by Person-to-Person Transmission.

作者信息

Huang Deyu, Jiang Yueping, Liu Xiaoping, Wang Bo, Shi Junming, Su Zhan, Wang Hui, Wang Ting, Tang Shuang, Liu Hanyun, Hu Zhihong, Deng Fei, Shen Shu

机构信息

Department of Infectious Diseases, Qilu hospital of Shandong University, Qingdao, People's Republic of China.

Department of infectious Diseases, Affiliated Hospital of Medical College Qingdao University, Qingdao, People's Republic of China.

出版信息

Am J Trop Med Hyg. 2017 Aug;97(2):396-402. doi: 10.4269/ajtmh.17-0059. Epub 2017 Jul 19.

DOI:10.4269/ajtmh.17-0059
PMID:28722592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5544100/
Abstract

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel phlebovirus that was identified to be the etiological pathogen of the emerging infectious disease, severe fever with thrombocytopenia syndrome (SFTS). SFTSV could be transmitted through tick bite. Transmission of SFTSV among humans has also been reported mainly through direct blood contact. In July 2014, a cluster of six suspected SFTS cases occurred in Shandong Province, China. In this cluster, both symptomatic and asymptomatic persons were included. By analyzing the clinical data and results of laboratory tests, and conducting the epidemiological interviews with the cases and their families, risk factors responsible for the transmission were evaluated. The findings suggested that SFTSV transmission among humans may cause asymptomatic infection via personal contact without blood exposure.

摘要

发热伴血小板减少综合征病毒（SFTSV）是一种新型白蛉病毒，被确定为新发传染病发热伴血小板减少综合征（SFTS）的病原体。SFTSV可通过蜱叮咬传播。据报道，SFTSV在人与人之间的传播主要也是通过直接血液接触。2014年7月，中国山东省发生了一起6例疑似SFTS病例的聚集性疫情。该聚集性疫情中包括有症状和无症状的人员。通过分析临床资料和实验室检测结果，并对病例及其家属进行流行病学访谈，评估了导致传播的危险因素。研究结果表明，SFTSV在人与人之间传播可能通过无血液暴露的人际接触导致无症状感染。