Unit of Andrology and Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Eur Rev Med Pharmacol Sci. 2017 Jun;21(2 Suppl):30-35.
Myo-inositol (MYO) usually represents a therapeutic option for female infertility associated with insulin resistance. Recently, several evidences are accumulating about the potential use of MYO for the treatment of male infertility. This article summarizes the rationale for MYO in the treatment of male infertility. In particular, it illustrates the potential antioxidant and prokinetic role of MYO, and its importance for the modulation of hormonal regulation. In the final part of the manuscript has been added a proposal for a clinical algorithm reserved for patients with asthenozoospermia, where probably MYO could exert specific pharmacological effects.
肌醇（MYO）通常是治疗与胰岛素抵抗相关的女性不孕的一种选择。最近，越来越多的证据表明肌醇可能用于治疗男性不育。本文总结了肌醇治疗男性不育的基本原理。特别是，它说明了肌醇的潜在抗氧化和促动力作用，及其对激素调节的重要性。在本文的最后部分，提出了一个针对弱精子症患者的临床算法建议，其中肌醇可能发挥特定的药理作用。
