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利用水蛭唾液治疗骨关节炎:一个具有启发性的观点。

Exploiting leech saliva to treat osteoarthritis: A provocative perspective.

作者信息

Cooper Edwin L, Mologne Natalie

机构信息

Laboratory of Comparative Immunology, Department of Neurobiology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095-1763, USA.

出版信息

J Tradit Complement Med. 2016 Dec 30;7(3):367-369. doi: 10.1016/j.jtcme.2016.11.005. eCollection 2017 Jul.

DOI:10.1016/j.jtcme.2016.11.005
PMID:28725633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5506651/
Abstract

Plant and animal-derived products are crucial components in complementary and alternative medicine. Although modern medicine has provided numerous innovations and advancements, these often fail to reveal new and dependable, inexpensive treatments nor real cures that are relatively free of adverse side effects. We present evidence that hirudotherapy, which utilizes leeches, improves certain diseases, including osteoarthritis. Osteoarthritis, a disease in joints, could benefit from use of medicinal peptides found in leech saliva, components of its immune system.

摘要

植物和动物源产品是补充和替代医学的关键组成部分。尽管现代医学已经带来了众多创新和进步,但这些往往未能揭示新的、可靠的、廉价的治疗方法,也未能找到相对无不良副作用的真正治愈方法。我们提供的证据表明,利用水蛭的水蛭疗法可以改善某些疾病,包括骨关节炎。骨关节炎是一种关节疾病,可能会受益于水蛭唾液中发现的药用肽,即其免疫系统的组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1792/5506651/03246b500dd5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1792/5506651/03246b500dd5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1792/5506651/03246b500dd5/gr1.jpg

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本文引用的文献

1
Opportunities for traditional Chinese medicine to address unmet challenges in modern healthcare.中医应对现代医疗保健中未满足挑战的机遇。
J Tradit Complement Med. 2015 Jan 7;5(1):2-4. doi: 10.1016/j.jtcme.2014.12.001. eCollection 2015 Jan.
2
Hirudotherapy in veterinary medicine.兽医学中的水蛭疗法。
Ann Parasitol. 2014;60(2):89-92.
3
Recommendations for the use of leeches in reconstructive plastic surgery.重建整形外科学中使用蚂蟥的建议。
Evid Based Complement Alternat Med. 2014;2014:205929. doi: 10.1155/2014/205929. Epub 2014 Feb 6.
4
Leech therapeutic applications.水蛭的治疗应用。
Indian J Pharm Sci. 2013 Mar;75(2):127-37.
5
A systematic review and meta-analysis of medical leech therapy for osteoarthritis of the knee.一项关于医用蚂蟥疗法治疗膝骨关节炎的系统评价和荟萃分析。
Clin J Pain. 2014 Jan;30(1):63-72. doi: 10.1097/AJP.0b013e31828440ce.
6
Leech therapy- a holistic approach of treatment in unani (greeko-arab) medicine.水蛭疗法——尤那尼(希腊-阿拉伯)医学中的一种整体治疗方法。
Anc Sci Life. 2011 Jul;31(1):31-5.
7
Three species of land leeches from Taiwan, Haemadipsa rjukjuana comb. n., a new record for Haemadipsa picta Moore, and an updated description of Tritetrabdella taiwana (Oka).来自台湾的三种陆生水蛭,新组合的日本山蛭(Haemadipsa rjukjuana comb. n.),平扁山蛭(Haemadipsa picta Moore)的新记录,以及台湾三带蛭(Tritetrabdella taiwana (Oka))的最新描述。
Zookeys. 2011(139):1-22. doi: 10.3897/zookeys.139.1711. Epub 2011 Oct 25.
8
[Medicinal leeches and hirudotherapy].[药用水蛭与水蛭疗法]
Turkiye Parazitol Derg. 2011;35(4):234-9. doi: 10.5152/tpd.2011.60.
9
Small bite, large impact-saliva and salivary molecules in the medicinal leech, Hirudo medicinalis.微小叮咬,巨大影响——医用水蛭(欧洲医蛭)中的唾液与唾液分子
Naturwissenschaften. 2011 Dec;98(12):995-1008. doi: 10.1007/s00114-011-0859-z. Epub 2011 Nov 9.
10
Clinical uses of the medicinal leech: a practical review.药用水蛭的临床应用:实用综述。
J Postgrad Med. 2011 Jan-Mar;57(1):65-71. doi: 10.4103/0022-3859.74297.