Zamfirov Kiril, Philippe Jacques
CUTR Sylvana, Service de gériatrie, CHUV, 1011 Lausanne.
Service d'endocrinologie, diabétologie, hypertension et nutrition, Département des spécialités de médecine, HUG, 1211 Genève 14.
Rev Med Suisse. 2017 Apr 26;13(560):917-921.
Musculoskeletal abnormalities are common and multiple in diabetic patients. They often result from pathologic changes in the microvasculature (microangiopathy), connective tissue, and peripheral nerves related to chronic hyperglycaemia. Their prevalence in patients with diabetes vary depending upon the diagnostic criteria, the study population and is generally correlated with poor glycaemic control and the occurrence of other complications of diabetes. These entities are important to recognize because they often respond to treatment, preventing pain and disability and improving quality of life.
肌肉骨骼异常在糖尿病患者中很常见且多种多样。它们通常源于与慢性高血糖相关的微血管(微血管病变)、结缔组织和周围神经的病理变化。其在糖尿病患者中的患病率因诊断标准、研究人群而异,并且通常与血糖控制不佳以及糖尿病的其他并发症的发生相关。认识到这些情况很重要,因为它们通常对治疗有反应,可预防疼痛和残疾并改善生活质量。